00960nam0-2200325---450-99000940780040332120110728103158.00-9512004-7-X000940780FED01000940780(Aleph)000940780FED0100094078020110728d2000----km-y0itay50------bafreGB--------001yy<<Les >>poésies de Bertran Carboneléditées par Michael J. RoutledgeBirminghamUniversity of Birmingham2000XXXIII, 198 p.24 cmAssociation internationale d'études occitanes6849.12Bertran Carbonel325105Routledge,Michael J.ITUNINAREICATUNIMARCBK990009407800403321849.12 BERT 1Dip.f.m.18095FLFBCFLFBCPoésies de Bertran Carbonel764513UNINA03674nam 2201045z- 450 991055773570332120240107235129.0(CKB)5400000000045986(oapen)https://directory.doabooks.org/handle/20.500.12854/76486(EXLCZ)99540000000004598620202201d2021 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierInsulin-Like Growth Factors in Development, Cancers and AgingBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20211 electronic resource (196 p.)3-0365-0770-1 3-0365-0771-X This Special Issue of Cells on “Insulin-Like Growth Factors in Development, Cancers and Aging” provides a collection of modern articles dealing with the role of insulin-like growth factors (IGF1) in cancer biology, aging and development. Featured articles explore basic and clinical aspects of the IGF1 system, including post-genomic analyses as well as novel approaches to target the IGF1 receptor (IGF1R) in oncology. The present Special Issue highlights some of the most important topics in the broad area of IGF research, including the role of IGF1 in aging and longevity, attempts to target the IGF1 axis in oncology, the role of IGF-binding proteins, structural aspects of IGF-II, etc. We trust that this assembly of articles will be of great help to students, basic researchers and practitioners.Research & information: generalbicsscBiology, life sciencesbicsscIGF-IIGF-IIinsulinIGF-IRIRstyrosine kinase receptorGPCRshybridsphosphorylationG-proteinsβ-arrestinsfunctional RTK/GPCR hybridnuclear translocationIGF-I receptorsignalingtargeted therapeuticsIGF-TrapIGF systemIGFBP-3IGFBP-3RTMEM219anti-tumoranti-metastaticagonistsmAb therapyIGF-1IGFBP-1older adultslongevityhealth-spanage-related diseasecognitive impairmentdiabetesmitochondriagrowth hormoneinsulin-like growth factor-1agingoxidative stresssenescencelongitudinal studyIGFBPmouse modelsskeletal muscleMSCsmyogenesisglucose regulated protein (GRP) 94insulin-like growth factorobligate chaperonehypertrophyatrophycachexiamuscle regenerationautophagyIGF-1Rinsulin receptorIR-Astructural studiesreceptor activationResearch & information: generalBiology, life sciencesWerner Haimedt1287877Werner HaimothBOOK9910557735703321Insulin-Like Growth Factors in Development, Cancers and Aging3020512UNINA