00764nam0-22002771i-450 99000798238040332120180409145024.0000798238FED01000798238(Aleph)000798238FED0100079823820050111d1994----km-y0itay50------baengComputational hydraulicsM. B. Abbott, A. W. MinneAldershotAshogote1994XVIII, 557 p.24 cmIdraulicaAbbott,Michael B.284380Minne,Anthony W.422071ITUNINAUNIMARCRICABK99000798238040332115 ID A/6-74DINIDDINIDComputational hydraulics752494UNINA02678nam 2200589 a 450 991043784790332120200520144314.01-283-93397-71-4614-5260-010.1007/978-1-4614-5260-7(CKB)3400000000093740(EBL)1081884(OCoLC)821823520(SSID)ssj0000810368(PQKBManifestationID)11456329(PQKBTitleCode)TC0000810368(PQKBWorkID)10827033(PQKB)11620405(DE-He213)978-1-4614-5260-7(MiAaPQ)EBC1081884(PPN)168302527(EXLCZ)99340000000009374020121219d2013 uy 0engur|n|---|||||txtccrAdvances in biology and therapy of multiple myelomaVolume 2Translational and clinical research /Nikhil C. Munshi, Kenneth C. Anderson, editors1st ed. 2013.New York Springer20131 online resource (290 p.)Description based upon print version of record.1-4899-8914-5 1-4614-5259-7 Includes bibliographical references and index.pt. I. Myeloma immune and antibody targets -- pt. II. New agents.Despite the advances in conventional, and novel agent and high dose chemotherapy, multiple myeloma remains incurable. In order to overcome resistance to current therapies and improve patient outcome, novel biologically-based treatment approaches are being developed. Current translational research in multiple myeloma focusing on the development of molecularly-based novel targeted single-agent and combination therapies has great promise to achieve high frequency and durable responses in the majority of patients. This volume will focus on biology of multiple myeloma, especially on oncogenomic changes, cell signaling pathways and intermediate molecules that are being investigated for development of novel therapies. The book will present newer developments, providing an emphasis on basic science, as well as its significant clinical impact.Multiple myelomaMedicineResearchMultiple myeloma.MedicineResearch.616.99418Munshi Nikhil C1064467Anderson Kenneth C876632MiAaPQMiAaPQMiAaPQBOOK9910437847903321Advances in biology and therapy of multiple myeloma2538380UNINA