00764nam0-22002771i-450-99000168330040332120051012134832.0000168330FED01000168330(Aleph)000168330FED0100016833020030910d1871----km-y0itay50------baitaProsciugamento del lago FucinoD. Alessandro TorloniaFirenzeLe Monnier1871125 p.25 cmBonifica631.6Torlonia,Alessandro<principe>130220ITUNINARICAUNIMARCBK99000168330040332160 631.6 B 43047FAGBCFAGBCProsciugamento del lago Fucino371704UNINA00923nam0-22002891i-450-99000525601040332120090707102713.00-8371-6034-0000525601FED01000525601(Aleph)000525601FED0100052560119990604d1972----km-y0itay50------baengf-------00---History of Palestine and Syria to the Macedonian Conquestby A.T. OlmsteadWestport (Conn.)Greenwood Press, Publishers1972XXXII, 664 p., 77 tav. di cui 1 rip.23 cm93322itaOlmstead,Albert Ten Eyck<1880-1945>327515ITUNINARICAUNIMARCBK990005256010403321933 OLM 1ANT. G.R. 1855FLFBCFLFBCHistory of Palestine and Syria to the Macedonian Conquest539333UNINA03473oam 2200709 c 450 991056302110332120250513224739.010.3726/b14026(CKB)5450000000174157(oapen)https://directory.doabooks.org/handle/20.500.12854/37746(PH02)9783631755129(oapen)doab37746(EXLCZ)99545000000017415720240525h20182003 uy 0gerurnnunnnannuutxtrdacontentcrdamediacrrdacarrierTaktisches Supply Chain PlanningPlanungsunterstützung durch deterministische und stochastische OptimierungsmodelleRoland Gabriel, Jens Thorn1st, New ed.Frankfurt a.MPH0220182018, c20031 online resource (248 p.), EPDFBochumer Beiträge zur Unternehmensführung65Peter Lang GmbH, Internationaler Verlag der Wissenschaften3-631-75512-0 Aus dem Inhalt: Grundlagen des Supply Chain Planning - Quantitative Ansätze zur Planungsunterstützung - Modellbildung für Produktions- und Logistiknetzwerke - Deterministische und stochastische Optimierung zum taktischen Supply Chain Planning.Planungsansätze an einem Beispiel illustriert und bewertet. Das taktische Supply Chain Planning bestimmt auf Basis einer prognostizierten Nachfrage die jeweiligen Produktmengen übergreifend von den Lieferanten über die Produktionsstandorte und Distributionslager bis hin zu den Kunden mit einem Planungshorizont von etwa einem Jahr. Da bei derartigen Planungsproblemen oftmals zahlreiche Standorte und Transportverbindungen zwischen den Standorten sowie vielfältige Produktarten zu berücksichtigen sind, ist eine Planungsunterstützung unter Einsatz quantitativer Methoden geboten. In dieser Arbeit werden unterschiedliche Ansätze zur Unterstützung des taktischen Supply Chain Planning diskutiert sowie ein stochastischer Ansatz zur Berücksichtigung einer mit Risiko behafteten Nachfrage entwickelt. Darüber hinaus werden die unterschiedlichen Ausgestaltungsmöglichkeiten der Planungsansätze an einem Beispiel illustriert und bewertet.Taktisches Supply Chain Planning Business studies: generalbicsscProduction & quality control managementbicsscPurchasing & supply managementbicsscDistribution & warehousing managementbicsscTransport industriesbicsscChaindeterministischedurchEinkaufenManagementOptimierungsmodellePlanningPlanungsunterstützungstochastischeSupplyTaktischesThornTransportBusiness studies: generalProduction & quality control managementPurchasing & supply managementDistribution & warehousing managementTransport industriesThorn Jensauth1300362Gabriel RolandedtThorn JensautPH02PH02BOOK9910563021103321Taktisches Supply Chain Planning3025524UNINA03089nam 2200469z- 450 991026114450332120210211(CKB)4100000002484647(oapen)https://directory.doabooks.org/handle/20.500.12854/42248(oapen)doab42248(EXLCZ)99410000000248464720202102d2016 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierBiomarkers of Alzheimer's Disease: The Present and the FutureFrontiers Media SA20161 online resource (218 p.)Frontiers Research Topics2-88945-041-4 Alzheimer disease (AD) is a neurodegenerative disorder characterized by significant cognitive deficits, behavioral changes, sleep disorders and loss of functional autonomy. AD represents the main cause of dementia and has become a major public health issue. In addition, the number of patients suffering from AD is growing rapidly as the population ages worldwide. Memory impairment is usually the earliest clinical and core symptom of this disease. The diagnosis at a late clinical stage is relatively easy. However, a delay in the diagnosis is damageable for the handling of patients in terms of optimal medical and social care. The actual interest of the scientific head-ways is to optimize the diagnosis in prodromal stage of the disease and to propose personalized therapeutic solutions to individual patients. New revised AD diagnostic criteria include early alteration of cerebrospinal fluid (CSF) biomarkers: decrease of amyloïd peptides (Aß42), and increase in tau and phosphorylated-tau (p-tau) protein concentration. This recognition of CSF biological biomarkers for the diagnosis of AD is a major step towards the "molecular" diagnosis and follow-up of the disease. Many issues are however still subject of debate. This e-book provides a comprehensive overview of the state of the art of fluid biomarkers for AD, e.g. which novel biomarkers should be implemented in clinical practice for diagnosis or for monitoring treatment or side effects, which ones are new for AD or related dementias or what is the potential of peripheral blood markers. Moreover, the e-Book provides practical guidelines how to optimally and efficiently develop and validate novel biomarker assays, and to document and control pre-analytical variation.Biomarkers of Alzheimer's DiseaseNeurosciencesbicsscAlzheimerbiomarkersBloodCSFDementiasdiagnosisdiscoverymethodsNeurochemistryValidationNeurosciencesTeunissen Charlotte Eauth1371814Lehmann Sylvain1965-authBOOK9910261144503321Biomarkers of Alzheimer's Disease: The Present and the Future3401455UNINA