03419nam 2200625 a 450 991046161770332120200520144314.01-283-14332-197866131433271-84816-367-3(CKB)2670000000095736(EBL)731333(OCoLC)738434150(SSID)ssj0000524181(PQKBManifestationID)12213183(PQKBTitleCode)TC0000524181(PQKBWorkID)10546100(PQKB)11062794(MiAaPQ)EBC731333(WSP)0000P630(Au-PeEL)EBL731333(CaPaEBR)ebr10479770(CaONFJC)MIL314332(EXLCZ)99267000000009573620110714d2011 uy 0engur|n|---|||||txtccrMicroRNAs in development and cancer[electronic resource] /editor, Frank J. SlackLondon Imperial College Press20111 online resource (300 p.)Molecular medicine and medicinal chemistry ;v. 1Description based upon print version of record.1-84816-366-5 Includes bibliographical references and index.Contents; Preface; 1 Introduction to Gene Regulation by Small RNAs Allison L. Abbott; 2 The Emerging Non-Coding RNA World Ahmad M. Khalil, Maite Huarte and John L. Rinn; 3 MicroRNAs in C. elegans Development Helge Großhans and Almuth E. Müllner; 4 MicroRNAs in Mammalian Development Andrea Ventura; 5 MicroRNAs in Hematopoietic Development Silvia Monticelli; 6 MicroRNAs Function as Tumor Suppressor Genes and Oncogenes Aurora Esquela-Kerscher; 7 Simultaneous Detection of Primary, Precursor and Mature MicroRNAs by qPCR Jinmai Jiang, Eun Joo Lee and Thomas D. Schmittgen8 Single Nucleotide Polymorphisms in MicroRNAs and MicroRNA Binding Sites with Roles in Cancer Lena J. Chin and Frank J. Slack9 MicroRNAs as Potential Diagnostics and Therapeutics Trupti Paranjape, Jae Choi and Joanne B.Weidhaas; 10 MicroRNA Target Prediction Isidore Rigoutsos and Aristotelis Tsirigos; 11 Non-Coding RNAs in Cancer - The Other Part of the Story Muller Fabbri and George A. Calin; IndexMicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development, all of which are processes that go awry in cancer. Thus, microRNAs have the ability to behave like oncogenes or tumor suppressors. In addition, their small size and molecular properties make them amenable as targets and therapeutics in cancer treatment. This book goes into detail on how microRNAs represenMolecular medicine and medicinal chemistry ;v. 1.CancerGenetic aspectsSmall interfering RNAElectronic books.CancerGenetic aspects.Small interfering RNA.572.88Slack Frank J961179MiAaPQMiAaPQMiAaPQBOOK9910461617703321MicroRNAs in development and cancer2179084UNINA01164nam0 22002773i 450 VAN0025064420240806101424.950978-88-15-24129-020220926d2012 |0itac50 baitaITAIT|||| |||||Disegnare il futuro con intelligenza antical'insegnamento del latino e del greco antico in Italia e nel mondoa cura di Luciano Canfora, Ugo CardinaleBolognail Mulino2012535 p.ill.22 cm001VAN000082562001 Percorsi210 BolognaIl Mulino1998-BolognaVANL000003CanforaLucianoVANV004599CardinaleUgoVANV089587Il MulinoeditoreVANV107886ITSOL20240906RICABIBLIOTECA DEL DIPARTIMENTO DI LETTERE E BENI CULTURALIIT-CE0103VAN07VAN00250644BIBLIOTECA DEL DIPARTIMENTO DI LETTERE E BENI CULTURALI07CONS Xa 351 07UBL2272 20220926 Disegnare il futuro con intelligenza antica1399207UNICAMPANIA