02741nas# 2200313 i 450 VAN000051220230306040215.2360035-670020020610b19472003 |0itac50 baitaIT|||| |||||aB|||||||||Rivista giuridica della circolazione e dei trasportiorgano della Commissione giuridica dell'Automobile club d'ItaliaRomaLEA1947-2003volumi24 cmVaria dimensione dal 1964 in 23 cm. - Pubbl. suppl. - Continuazione di: Rassegna giuridica della circolazione stradale : nuova serie della Giustizia automobilisticaCircolazione stradaleLegislazionePeriodiciVANC032370FIRomaVANL000360343.4509305Diritto dei trasporti. Italia. Pubblicazioni in serie20L'editrice dell'automobileVANV111695650ITSOL20231222RICAhttp://www.rivistagiuridica.aci.it./index.php?id=2http://www.rivistagiuridica.aci.it./index.php?id=2BIBLIOTECA DEL DIPARTIMENTO DI GIURISPRUDENZAIT-CE0105VAN001951-1952; 1954-1959; 1994-1998;ARCHIVIO, arm. 1 ; SALA BIANCA sc. 1 ;VAN0000512BIBLIOTECA DEL DIPARTIMENTO DI GIURISPRUDENZA001951-1952; 1954-1959;00RIV ARCHIVIO, arm. 1 1951 00FTN6233 20131014 00RIV ARCHIVIO, arm. 1 1952 00FTN6234 20131014 00RIV ARCHIVIO, arm. 1 1954 00FTN6235 20131014 00RIV ARCHIVIO, arm. 1 1955 00FTN6236 20131014 00RIV ARCHIVIO, arm. 1 1956 00FTN6237 20131014 00RIV ARCHIVIO, arm. 1 1957 00FTN6238 20131014 00RIV ARCHIVIO, arm. 1 1958 00FTN7750 20131014 00RIV ARCHIVIO, arm. 1 1959 00FTN7751 20131014 BIBLIOTECA DEL DIPARTIMENTO DI GIURISPRUDENZA001994-1998;00RIV SALA BIANCA sc. 1 1994 00RIV1860 20131213 00RIV SALA BIANCA sc. 1 1995 00RIV1861 20131213 00RIV SALA BIANCA sc. 1 1996 00RIV1862 20131213 00RIV SALA BIANCA sc. 1 1997 00RIV1863 20131213 00RIV SALA BIANCA sc. 1 1998 00RIV1864 20131213 Rivista giuridica della circolazione e dei trasporti789162UNICAMPANIA04825nam 22006375 450 991086319270332120251223155131.03-030-53868-010.1007/978-3-030-53868-2(CKB)4100000011457761(DE-He213)978-3-030-53868-2(MiAaPQ)EBC6355545(PPN)250223368(MiAaPQ)EBC6355490(MiAaPQ)EBC29092558(EXLCZ)99410000001145776120200919d2020 u| 0engurnn|008mamaatxtrdacontentcrdamediacrrdacarrierDamage-Associated Molecular Patterns in Human Diseases Volume 2: Danger Signals as Diagnostics, Prognostics, and Therapeutic Targets /by Walter Gottlieb Land1st ed. 2020.Cham :Springer International Publishing :Imprint: Springer,2020.1 online resource (XXXIX, 629 p. 45 illus. in color.) 3-030-53867-2 Part I. Prologue -- Perspectives of the Danger/Injury Model in Immunology -- Part II. A Select, Clinically Oriented Update of Topics Presented in “Damage-Associated Molecular Patterns in Human Diseases”; Volume 1: Injury-Induced Innate Immune Responses -- Pattern Recognition Molecules -- The Growing World of DAMPs -- The Growing Clinical Relevance of Cellular Stress Responses and Regulated Cell Death -- DAMP-Promoted Efferent Innate Immune Responses in Human Diseases: Inflammation -- DAMP-Promoted Efferent Innate Immune Responses in Human Diseases: Fibrosis -- Part III. DAMPs and SAMPs in Traumatic Disorders, Atherosclerosis, and Cerebro-Cardiovascular Diseases -- DAMPs and SAMPs as Molecular Biomarkers, Therapeutic Targets, and Therapeutics -- DAMP-Controlled and Uncontrolled Responses to Trauma: Wound Healing and Polytrauma -- Solid Organ Injury -- Atherosclerosis -- Cerebro - Cardiovascular Diseases -- Part IV. Epilogue -- The “DAMPome” as a Key Player in the Pathogenesis of Human Diseases.This book is a continuance of the topic: “DAMPs in Human Diseases”, the basics of which were described in a first volume by the same author. This second volume presents our current understanding of the impact of sterile stress/injury-induced innate immune responses on the etiopathogenesis of human diseases by focusing on those diseases that are pathogenetically dominated by DAMPs, i.e., on polytrauma, various solid organ injuries (brain, lung, kidney, liver), atherosclerosis, and cerebro-cardiovascular diseases. Our growing understanding of the pathogenetic function of activating DAMPs and suppressive DAMPs (“SAMPs”) is used as a point of departure to explore how these molecules can be used as biomarkers to extend and improve current diagnostic and prognostic modalities. Moreover, this new knowledge about the pathogenetic function of DAMPs and SAMPs is taken as a sound and plausible reason for discussing their implications for present and future treatment of the diseases addressed here. In this context, the focus is on the potential of DAMPs as future therapeutic targets and SAMPs as future therapeutics, applied in strict compliance with safety precautions, as also recommended in this work. The book is intended for professionals from all medical and paramedical disciplines who are interested in applying innovative data from inflammation and immunity research to clinical practice. The readership will include practitioners and clinicians working in the broad field of acute and chronic inflammatory/fibrotic diseases, in particular, traumatologists and intensivists; neurologists and neurosurgeons; cardiologists and cardiac surgeons; pulmonologists and thoracic surgeons; vascular surgeons; nephrologists; gastroenterologists and hepatologists; and pharmacists. Also available: Damage-Associated Molecular Patterns in Human Diseases - Vol. 1: Injury-Induced Innate Immune Responses .Internal medicineAllergyImmunologyMedicineResearchBiologyResearchInternal MedicineAllergologyImmunologyBiomedical ResearchInternal medicine.Allergy.Immunology.MedicineResearch.BiologyResearch.Internal Medicine.Allergology.Immunology.Biomedical Research.617.1Land W(Walter),909257MiAaPQMiAaPQMiAaPQBOOK9910863192703321Damage-associated molecular patterns in human diseases2034040UNINA