1.

Record Nr.

UNISOBSOBE00053901

Autore

Clark, Jonathan C. D.

Titolo

The language of liberty, 1660-1832 : political discourse and social dynamics in the Anglo-American world / J. C. D. Clark

Pubbl/distr/stampa

Cambridge : Cambridge University Press, 1994

ISBN

052144957X

Descrizione fisica

XVIII,404 p. ; 23 cm

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

2.

Record Nr.

UNINA9910458470203321

Titolo

Translation of addictions science into practice [[electronic resource] /] / edited by Peter M. Miller and David J. Kavanagh

Pubbl/distr/stampa

Amsterdam ; ; Boston, : Elsevier/Pergamon, 2007

ISBN

1-281-05582-4

9786611055820

0-08-048981-8

Edizione

[1st ed.]

Descrizione fisica

1 online resource (513 p.)

Altri autori (Persone)

MillerPeter M <1942-> (Peter Michael)

KavanaghDavid John

Disciplina

616.86/06 22

616.8606

Soggetti

Drug abuse - Physiological aspects

Substance abuse - Physiological aspects

Drug abuse - Treatment

Substance abuse - Treatment

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.



Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Front cover; Translation of Addictions Science into Practice; Copyright page; Table of Contents; List of Contributors; Preface; Section I: Genetics and Neuroscience; Chapter 1. The Interplay between Genotype and Gene Expression in Human Brain: What Can it Teach Us about Alcohol Dependence?; Drug and Alcohol Abuse; Future Directions; Concluding Remarks; Acknowledgments; References; Chapter 2. Common Genetic Influences on Antisociality and Addictions: Implications for Clinical Science and Practice; Comorbidity of Addictions and Antisociality: An Introduction

Shared Genetic Vulnerabilities to Antisociality and AddictionsMolecular Genetics of Antisociality and Addictions: Examples from the Study of Alcoholism; Implications of Common Genetic Influences of Antisocial Personality and Addictions for Conceptualizing and Classifying Psychopathology; From Genes to Clinical Practice: Implications of Genetic Research for Advancing Clinical Care; Summary and Conclusions; References; Chapter 3. Opioids, Pain and Addiction: Cause and Consequence; Opioid-Induced Hyperalgesia; Implications for Opioid Dependence Treatment; Future Directions; General Conclusion

ReferencesChapter 4. Imbalance between Neuroexcitatory and Neuroinhibitory Amino Acids causes Craving for Ethanol: From Animal to Human being Studies; Introduction; Effects of Ethanol on Glutamate; Ethanol Withdrawal; Multiple Ethanol Withdrawal; Acamprosate and Repeated Ethanol Withdrawal; Conditioning Associated with Ethanol; Excitatory Amino Acids and Ethanol in Humans; Clinical Implications; References; Chapter 5. Cannabis and the Brain: Implications of Recent Research; Psychiatric Symptoms Associated with Cannabis; Cannabis and Schizophrenia; Summary and Future Directions; References

Section II: PharmacotherapyChapter 6. The Plasticity of Alcohol Addiction Suggests Novel Approaches to Pharmacological Intervention; Neurobiology of Alcohol Addiction; Glutamatergic System; Glutamate and Alcohol; Ethanol and the Post-Synaptic Density; Metabotropic Glutamate Receptors; References; Chapter 7. Pharmacotherapies for the Treatment of Alcohol Dependence: Current and on the Horizon; Epidemiology; Alcohol Withdrawal and Detoxification; Relapse Prevention; Disulfiram; Naltrexone; Acamprosate; Treatment Options on the Horizon

Medication Compliance and Its Impact on Alcohol PharmacotherapyConclusions and Future Directions; References; Chapter 8. Agonist Treatment for Stimulant Abuse and Dependence; Relevant Science, Introduction and Background; Immediate Implications for Prevention, Assessment or Treatment Developments; Speculation on Future Directions for Translational Developments; References; Chapter 9. Topiramate-Induced Neuromodulation of Cortico-Mesolimbic Dopamine: Implications for the Treatment of Nicotine and Alcohol Dependence; Nicotine and Alcohol Dependence:The Problem of Comorbidity

Topiramate: A Promising new Vista

Sommario/riassunto

Recent advances in the understanding of the genetic, neurochemical, behavioral and cultural underpinnings of addiction have led to rapid advances in the understanding of addiction as a disease.  In fact, advances in basic science and the development of new pharmacological and behavioral therapies associated with them are appearing faster than can be assimilated not only by clinical researchers but practitioners and policy makers as well.  Translation of science-based addictions knowledge into improved prevention, assessment and treatment, and communication of these changes to researchers and p