1.

Record Nr.

UNISALENTO991003803329707536

Autore

Calladine, C.R.

Titolo

Understanding DNA : the molecule & how it works / by C.R. Calladine ...[et al.]

Pubbl/distr/stampa

San Diego : Elsevier Academic Press, 2004

ISBN

9780121550899

Edizione

[3rd ed.]

Descrizione fisica

xiii, 334 p. : ill. ; 25 cm

Classificazione

LC QP624.C34

Disciplina

572.8/6

Soggetti

Molecular biology

DNA

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references and index

Nota di contenuto

Ch. 1. An Introduction to Molecular Biology for Non-Scientists -- Ch. 2. Why a Helix? -- Ch. 3. Different Kinds of Double Helix -- Ch. 4. Twisting and Curving -- Ch. 5. Curving in Three Dimensions -- Ch. 6. DNA Supercoiling -- Ch. 7. The Assembly of DNA into Chromosomes -- Ch. 8. Specific DNA-Protein Interactions -- Ch. 9. Methods Used to Study the Structure of DNA -- Ch. 10. DNA in Disease, Diagnostics and Medicine -- Ch. 11. Cytosine methylation and DNA epigenetics -- Postscript. App. 1. Notes on the Derivation of Some Technical Terms -- App. 2. The Chemical Theory of Base-stacking Interactions in DNA. -- App. 3. How to modify Gene Expression Using Anti-sense Oligonucleotides, Ribozymes or Small Interfering-RNA -- Answers to Selected Exercises