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1. |
Record Nr. |
UNISALENTO991003726759707536 |
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Autore |
Guerra, Alessandro |
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Titolo |
Il vile satellite del trono : Lorenzo Ignazio Thjulen: un gesuita svedese per la controrivoluzione / Alessandro Guerra |
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Pubbl/distr/stampa |
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Milano : F. Angeli, [ 2004] |
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ISBN |
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Descrizione fisica |
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Collana |
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Disciplina |
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Soggetti |
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Thjulen, Lorenzo Ignazio |
Thjulen, Lorenzo Ignazio |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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2. |
Record Nr. |
UNISALENTO991003214169707536 |
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Autore |
Beretta, Marco |
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Titolo |
A history of non-printed science : a select catalogue of the Waller Collection / by Marco Beretta |
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Pubbl/distr/stampa |
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Uppsala ; Stockholm : Almqvist & Wiksell [distributore], [1993] |
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ISBN |
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Descrizione fisica |
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Collana |
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Acta Bibliothecae R. Universitatis Upsaliensis ; 31 |
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Soggetti |
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Scienze - Bibliografia - Cataloghi |
Waller, Erik (1875-1955) - Biblioteche - Cataloghi |
Uppsala - Biblioteca universitaria - Biblioteca Walleriana - Cataloghi |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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3. |
Record Nr. |
UNISALENTO991000298059707536 |
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Autore |
Lewis, G.L. |
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Titolo |
Teach yourself turkish / by G.L. Lewis |
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Pubbl/distr/stampa |
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London : English universities press, 1953 |
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Descrizione fisica |
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Collana |
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Soggetti |
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Lingua turca - Grammatica |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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4. |
Record Nr. |
UNINA9910960327803321 |
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Titolo |
Virtual ADMET assessment in target selection and maturation / / edited by B. Testa and L. Turski |
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Pubbl/distr/stampa |
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Amsterdam ; ; Washington, DC, : IOS Press, c2006 |
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ISBN |
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1-280-81056-4 |
9786610810567 |
1-4294-6772-X |
1-60750-219-4 |
600-00-0604-7 |
1-4337-0155-3 |
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Edizione |
[1st ed.] |
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Descrizione fisica |
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1 online resource (268 p.) |
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Collana |
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Solvay Pharmaceuticals Conferences, , 1566-7685 ; ; v. 6 |
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Altri autori (Persone) |
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TestaBernard |
TurskiLechoslaw |
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Disciplina |
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Soggetti |
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Drug development - Computer simulation |
Pharmacology |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Organized May 11-13th, 2005 in Lucerne, Switzerland. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Preface; List of Contributors; Contents; Conference Preface; The Risky Business of Developing Drugs; Benefits and Limits of in Silico Predictions; Musings on ADME Predictions and Molecular Structure; Lipophilicity: Its Calculation and Application in ADMET Predictions; Interpretation of the Role of the Electrotopological State and Molecular Connectivity Indices in the Prediction of Physical Properties and ADME-Tox Behavior - Case Study: Human Plasma Protein Binding; Molecular Descriptors for Predicting ADMET Properties; Molecular Fields to Assess Recognition Forces and Property Spaces |
Extracting Pharmacophores from Bio-Active MoleculesIn Silico Models for Human Bioavailability; In Silico Models to Predict Brain Uptake; Algorithms to Predict Affinity for Transporters; Predicting Affinity for and Metabolism by Cytochromes P450; Expert Systems to Predict Biotransformation; Expert Systems to Predict Toxicity; From in Vivo to in Vitro/in Silico ADME: Progress and Challenges; Author Index |
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Sommario/riassunto |
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Today, biologists and medicinal chemists realize that there is a strong relationship between pharmacodynamic (what the drug does to the organism) and pharmacokinetic (what the organism does to the drug) effects. A significant contributing factor to the evolution in drug discovery was the methodological and technological revolution with the advent of combinatorial chemistry, high-throughput screening and profiling, and in silico prediction of target-based activity and ADMET (absorption, distribution, metabolism, excretion and toxicity) properties. High-throughput screening and in silico methods |
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