1.

Record Nr.

UNINA9910231247003321

Autore

Feng Zhang

Titolo

Genome Editing in Neurosciences [[electronic resource] /] / edited by Rudolf Jaenisch, Feng Zhang, Fred Gage

Pubbl/distr/stampa

Springer Nature, 2017

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017

ISBN

3-319-60192-X

Edizione

[1st ed. 2017.]

Descrizione fisica

1 online resource (XI, 123 p. 16 illus. in color.)

Collana

Research and Perspectives in Neurosciences, , 0945-6082

Disciplina

611.01816

599.935

Soggetti

Human genetics

Neurosciences

Biomedical engineering

Human Genetics

Biomedical Engineering/Biotechnology

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

Introduction -- In vitro modeling of complex neurological diseases -- Aquatic model organisms in neurosciences : the genome editing revolution -- Genome-wide genetic screening in the mammalian CNS -- CRISPR/Cas9-mediated Knockin and Knockout in Zebrafish -- Dissecting the role of synaptic proteins with CRISPR -- Recurrently Breaking Genes in Neural Progenitors: Potential Roles of DNA Breaks in Neuronal Function, Degeneration and Cancer -- Neuroscience research using non-human primate models and genome editing -- Multiscale genome engineering: Genome-wide screens and targeted approaches -- Using Genome Engineering to Understand Huntington’s Disease -- Therapeutic gene editing in muscles and muscle stem cells.

Sommario/riassunto

This book is open access under a CC BY 4.0 license. Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability



to tackle the complexity of the brain. This Colloque Médecine et Recherche has brought together experts from around the world that are applying genome editing to address important challenges in neuroscience, including basic biology in model organisms that has the power to reveal systems-level insight into how the nervous system develops and functions as well as research focused on understanding and treating human neurological disorders.

2.

Record Nr.

UNISALENTO991003554829707536

Autore

Cavalcoli, Aldo

Titolo

Scegliere il personal computer / Aldo Cavalcoli ; a cura di Virginio Sala

Pubbl/distr/stampa

Milano : Arnoldo Mondadori, c1983

Descrizione fisica

158 p. : ill. ; 24 cm

Collana

Edizioni elettroniche Mondadori. Serie Libri

Altri autori (Persone)

Sala, Virginio

Disciplina

004

Soggetti

Computers

Lingua di pubblicazione

Italiano

Formato

Materiale a stampa

Livello bibliografico

Monografia



3.

Record Nr.

UNICASVIA0032619

Titolo

4 : Dughet-Gillet / E. Benezit

Pubbl/distr/stampa

Paris, : Grund, 1976

ISBN

2700001524

Descrizione fisica

728 p. ; 25 cm.

Lingua di pubblicazione

Francese

Formato

Materiale a stampa

Livello bibliografico

Monografia