1.

Record Nr.

UNISA996465860103316

Titolo

Computational Life Sciences [[electronic resource] ] : First International Symposium, CompLife 2005, Konstanz, Germany, September 25-27, 2005, Proceedings / / edited by Michael R. Berthold, Robert Glen, Kay Diederichs, Oliver Kohlbacher, Ingrid B. Fischer

Pubbl/distr/stampa

Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2005

Edizione

[1st ed. 2005.]

Descrizione fisica

1 online resource (XII, 280 p.)

Collana

Lecture Notes in Bioinformatics, , 2366-6331 ; ; 3695

Disciplina

572.80285

Soggetti

Life sciences

Information storage and retrieval systems

Medical informatics

Database management

Application software

Proteins

Life Sciences

Information Storage and Retrieval

Health Informatics

Database Management

Computer and Information Systems Applications

Protein Biochemistry

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Bibliographic Level Mode of Issuance: Monograph

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Systems Biology -- Structural Protein Interactions Predict Kinase-Inhibitor Interactions in Upregulated Pancreas Tumour Genes Expression Data -- Biochemical Pathway Analysis via Signature Mining -- Recurrent Neuro-fuzzy Network Models for Reverse Engineering Gene Regulatory Interactions -- Data Analysis and Integration -- Some Applications of Dummy Point Scatterers for Phasing in Macromolecular X-Ray Crystallography -- BioRegistry: A Structured Metadata Repository for Bioinformatic Databases -- Robust Perron Cluster Analysis for



Various Applications in Computational Life Science -- Structural Biology -- Multiple Alignment of Protein Structures in Three Dimensions -- Protein Annotation by Secondary Structure Based Alignments (PASSTA) -- MAPPIS: Multiple 3D Alignment of Protein-Protein Interfaces -- Genomics -- Frequent Itemsets for Genomic Profiling -- Gene Selection Through Sensitivity Analysis of Support Vector Machines -- The Breakpoint Graph in Ciliates -- Computational Proteomics -- ProSpect: An R Package for Analyzing SELDI Measurements Identifying Protein Biomarkers -- Algorithms for the Automated Absolute Quantification of Diagnostic Markers in Complex Proteomics Samples -- Detection of Protein Assemblies in Crystals -- Molecular Informatics -- Molecular Similarity Searching Using COSMO Screening Charges (COSMO/3PP) -- Increasing Diversity in In-silico Screening with Target Flexibility -- Multiple Semi-flexible 3D Superposition of Drug-Sized Molecules -- Molecular Structure Determination and Simulation -- Efficiency Considerations in Solving Smoluchowski Equations for Rough Potentials -- Fast and Accurate Structural RNA Alignment by Progressive Lagrangian Optimization -- Visual Analysis of Molecular Conformations by Means of a Dynamic Density Mixture Model -- Distributed Data Mining -- Distributed BLAST in a Grid Computing Context -- Parallel Tuning of Support Vector Machine Learning Parameters for Large and Unbalanced Data Sets -- The Architecture of a Proteomic Network in the Yeast.