1.

Record Nr.

UNISA996465732503316

Titolo

Computational Methods in Systems Biology [[electronic resource] ] : 7th International Conference, CMSB 2009 / / edited by Pierpaolo Degano, Roberto Gorrieri

Pubbl/distr/stampa

Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2009

ISBN

3-642-03845-X

Edizione

[1st ed. 2009.]

Descrizione fisica

1 online resource (X, 329 p.)

Collana

Lecture Notes in Bioinformatics ; ; 5688

Classificazione

BIO 110f

SS 4800

Disciplina

570

Soggetti

Life sciences

Computers

Bioinformatics

Computer simulation

Numerical analysis

Life Sciences, general

Theory of Computation

Computational Biology/Bioinformatics

Simulation and Modeling

Computation by Abstract Devices

Numeric Computing

Bologna (2009)

Kongress.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Bibliographic Level Mode of Issuance: Monograph

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Prediction of Protein-Protein Interacting Sites: How to Bridge Molecular Events to Large Scale Protein Interaction Networks -- The Equivalence between Biology and Computation -- BlenX4Bio – BlenX for Biologists -- Modelling Biological Clocks with Bio-PEPA: Stochasticity and Robustness for the Neurospora crassa Circadian Network -- Quantitative Pathway Logic for Computational Biology -- A Prize-Collecting Steiner Tree Approach for Transduction Network Inference



-- Formal Analysis of the Genetic Toggle -- Control Strategies for the Regulation of the Eukaryotic Heat Shock Response -- Computing Reachable States for Nonlinear Biological Models -- On Coupling Models Using Model-Checking: Effects of Irinotecan Injections on the Mammalian Cell Cycle -- The ?-Lattice: Decidability Boundaries for Qualitative Analysis in Biological Languages -- Approximation of Event Probabilities in Noisy Cellular Processes -- Equivalence and Discretisation in Bio-PEPA -- Improved Parameter Estimation for Completely Observed Ordinary Differential Equations with Application to Biological Systems -- A Bayesian Approach to Model Checking Biological Systems -- Dynamic Compartments in the Imperative ?-Calculus -- Probabilistic Approximations of Signaling Pathway Dynamics -- A Reduction of Logical Regulatory Graphs Preserving Essential Dynamical Properties -- On the Use of Stochastic Petri Nets in the Analysis of Signal Transduction Pathways for Angiogenesis Process -- CSL Model Checking of Biochemical Networks with Interval Decision Diagrams -- Qualitative Transition Systems for the Abstraction and Comparison of Transient Behavior in Parametrized Dynamic Models.

Sommario/riassunto

This book constitutes the refereed proceedings of the 7th International Conference on Computational Methods in Systems Biology, CMSB 2009, held in Bologna, Italy, August 31 - September 1, 2009. The 18 revised full papers presented together with the summaries of 3 invited papers were carefully reviewed and selected from more than 45 submissions. The papers cover theoretical or applied contributions that are motivated by a biological question focusing on modeling approaches, including process algebra, simulation approaches, analysis methods, in particular model checking and flux analysis, and case studies.