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Record Nr. |
UNISA996426332603316 |
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Autore |
Flamand Louis |
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Titolo |
Human herpesviruses HHV-6A, HHV-6B, and HHV-7 : diagnosis and clinical management / / Louis Flamand, Quebec, PQ, Canada [and three others] |
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Pubbl/distr/stampa |
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Oxford : , : Elsevier, , 2014 |
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ISBN |
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Edizione |
[3rd ed.] |
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Descrizione fisica |
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1 online resource (362 p.) |
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Disciplina |
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Soggetti |
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Herpesviruses |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Front Cover; Human Herpesviruses HHV-6A, HHV-6B, and HHV-7; Copyright Page; Contents; List of Contributors; Foreword by Philip E. Pellett; Foreword by Yoshizo Asano; Dedication; 1 HHV-6A and HHV-6B Officially Classified as Distinct Viruses; Introduction and Classification History; Distinct Epidemiology and Disease Associations; Acknowledgment; References; 2 Practical Diagnostic Procedures for HHV-6A, HHV-6B, and HHV-7; An Overview of Diagnostic Strategies; Objectives; Direct and Indirect Approaches; Specimens; Methods of Direct Diagnosis; Cell Culture; Antigen Detection |
Nucleic Acid Detection, Quantitation, and SequencingDetection of DNA by in situ Hybridization; Detection and Quantitation of DNA by PCR and Real-Time PCR; Detection and Quantitation of Transcripts by RT-PCR; Nucleotide Sequencing; Differential Diagnosis of HHV-6A and HHV-6B Infection; Antiviral Susceptibility Assays; Serologic Methods; Techniques; Viral Antigens Used for Serologic Testing; Characterization of Specific Antibodies; Indications and Findings; Primary Infection; Chronic Infection and Reactivations; Chromosomal Integration; Epidemiology; Therapeutic Follow-Up |
Conclusions: Practical Management of DiagnosisReferences; 3 Pathologic Features of HHV-6A, HHV-6B, and HHV-7 Infection (Light and Electron Microscopy); Introduction; Viral Infection and Pathogenesis; Morphogenesis of Cell and Tissue Lesions; Anatomic |
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(Systemic) Pathology of Tissues and Organs; Diagnostic Criteria; Pathologic Lesions in Primary Infection; Viral Persistence and Chromosomal Integration; Pathologic Lesions in Reactivation and Endogenous Reinfection; Morphology of Organ Systems in Reactivated Infections; Cardiovascular System; Respiratory System; Gastrointestinal System |
Liver, Biliary System, and PancreasHematopoietic and Lymphatic System; Endocrine System; Urogenital System; Skin and Soft Tissues; Central Nervous System; Autoimmune Disorders; Virus Interactions; References; 4 HHV-6A, HHV-6B, and HHV-7 in Febrile Seizures and Status Epilepticus; Introduction; History of HHV-6, Roseola Infantum, and Febrile Seizures; HHV-6B and Febrile Seizures; HHV-6B and Recurrence of Febrile Seizures; HHV-6A, HHV-6B, and HHV-7 in Children with Febrile Status Epilepticus; HHV-6 and HHV-7 and Temporal Lobe Epilepsy; HHV-6 Encephalitis in Immunocompetent Patients |
HHV-6 and Limbic Encephalitis in Immunosuppressed PatientsConclusions; References; 5 HHV-6A, HHV-6B, and HHV-7 in Encephalitis; Introduction; General Aspects and Neurotropism of Human Herpesvirus 6A Infection; General Aspects of Human Herpesvirus 6B Infection; Importance of Chromosomally Integrated HHV-6 in Neurological Conditions; Human Herpesvirus 7; Clinical Presentation of HHV-6- or HHV-7-Associated Encephalitis; Encephalitis Following a Primary HHV-6 or HHV-7 Infection in Immunocompetent Individuals; Encephalitis Following Reactivation of HHV-6 or HHV-7 in Immunocompromised Patients |
Pathology and Pathogenesis |
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Sommario/riassunto |
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Completely revised and updated, Human Herpesviruses HHV-6A, HHV-6B & HHV-7, Third Edition, delivers a contemporary and thorough review of HHV-6, beginning with foundational explorations of classification, molecular biology, and chromosomal integration of the virus, through to clinical details, including pathologic features of infection, and clinical effects on various organ systems. The work now includes coverage of HHV-7, a virus that remains underestimated in transplant reactivation, seizures, and encephalitis. The book examines the role of HHV-6 in myriad diseases, includi |
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