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1. |
Record Nr. |
UNISA996418642603316 |
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Titolo |
The petition of both Houses of Parliament presented to his Majestie at York, the 23 of May, 1642 : concerning the disbanding of his guard, with the three votes of both Houses of the 20, and His Majesties answer thereunto |
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Pubbl/distr/stampa |
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[London], : Printed first at York, and now reprinted [sic] at London, by A.N. for Edward Husbands ..., 1642 |
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Descrizione fisica |
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Testo elettronico (PDF) ([8] p.) |
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Altri autori (Persone) |
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Charles, King of England, <1600-1649.> |
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Disciplina |
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Soggetti |
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Gran Bretagna Storia Guerra civile 1642-1649 |
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Lingua di pubblicazione |
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Formato |
Risorsa elettronica |
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Livello bibliografico |
Monografia |
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Note generali |
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Imperfetto: pagine macchiate con perdita di stampa. |
Altri autori di contributi: Charles I, King of England, 1600-1649. |
Riproduzione dell'originale nella University of Illinois (Urbana-Champaign Campus). Library. |
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2. |
Record Nr. |
UNINA9910809152503321 |
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Titolo |
DNA deamination and the immune system : AID in health and disease / / editors, Sebastian Fugmann, Marilyn Diaz, Nina Papavasiliou |
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Pubbl/distr/stampa |
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London, : Imperial College Press, 2011 |
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ISBN |
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1-283-14344-5 |
9786613143440 |
1-84816-593-5 |
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Edizione |
[1st ed.] |
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Descrizione fisica |
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1 online resource (232 p.) |
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Collana |
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Molecular medicine and medicinal chemistry ; ; v. 3 |
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Altri autori (Persone) |
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FugmannSebastian |
DiazMarilyn |
PapavasiliouNina |
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Disciplina |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Preface; Contents; List of Tables; List of Figures; Chapter 1 Introduction; Chapter 2 Switch Regions, ChromatinAccessibility and AID Targeting; Chapter 3 Cis-Regulatory Elements that Target AID to Immunoglobulin Loci; Chapter 4 Partners in Diversity: The Search for AID Co-Factors; Chapter 5 Resolution of AID Lesions in Class Switch Recombination; Chapter 6 Error-Prone and Error-Free Resolution of AID Lesions in SHM; Chapter 7 Regulatory Mechanisms of AID Function; Chapter 8 AID in Immunodeficiency and Cancer; Chapter 9 AID in Aging and in Autoimmune Disease; Index |
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Sommario/riassunto |
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This book covers the current understanding of the role of activation-induced cytidine deaminase (AID) in the generation of antibody response to antigenic challenge. Since the discovery of AID, and the genetic demonstration of its role in somatic hypermutation and class-switch recombination of antibody genes, much has been learned about the biochemistry of this enzyme. However, some key questions remain hotly contested, such as: how does this enzyme get to the antibody locus leaving the rest of the genome intact, and why are DNA repair pathways which normally repair deamination events co-opted |
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