Business Process Management [[electronic resource] ] : 18th International Conference, BPM 2020, Seville, Spain, September 13–18, 2020, Proceedings / / edited by Dirk Fahland, Chiara Ghidini, Jörg Becker, Marlon Dumas

• Record Nr.: UNISA996418290003316
• Pubbl/distr/stampa: Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020
• ISBN: 3-030-58666-9
• Edizione: [1st ed. 2020.]
• Descrizione fisica: 1 online resource (XLIII, 524 p. 397 illus., 80 illus. in color.)
• Collana: Information Systems and Applications, incl. Internet/Web, and HCI ; ; 12168
• Disciplina: 658.05
• Soggetti: Information storage and retrieval; Application software; Management information systems; Industrial management; E-commerce; Artificial intelligence; Information Storage and Retrieval; Information Systems Applications (incl. Internet); Business Process Management; e-Commerce/e-business; Artificial Intelligence
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Includes index.
• Nota di contenuto: Keynotes -- Process Minding: Closing the Big Data Gap -- Characterizing Machine Learning Processes: A Maturity Framework -- Foundations -- Extending Temporal Business Constraints with Uncertainty -- Petri Nets with Parameterised Data Modelling and Verification -- Socially-Aware Business Process Redesign -- Incentive Alignment of Business Processes -- PRIPEL: Privacy-Preserving Event Log Publishing Including Contextual Information -- A Framework for Estimating Simplicity of Automatically Discovered Process Models Based on Structural and Behavioral Characteristics -- Online Process ; Monitoring Using Incremental State-Space Expansion: An Exact Algorithm -- Engineering -- Looking for Meaning: Discovering Action-Response-Effect Patterns in Business Processes -- Extracting Annotations from Textual Descriptions of Processes -- Analyzing Process Concept Drifts Based on Sensor Event Streams During Runtime -- TADE: Stochastic Conformance Checking using Temporal Activity Density Estimation -- Predictive Business Process Monitoring via Generative Adversarial Nets: The Case of Next Event Prediction -- Exploring Interpretable Predictive Models for Business Processes -- Triggering Proactive Business Process Adaptations via Online Reinforcement Learning -- Video-to-Model: Unsupervised Trace Extraction from Videos for Process Discovery and Conformance Checking in Manual Assembly -- Enhancing Event Log Quality: Detecting and Quantifying Timestamp Imperfections -- Automatic Repair of Same-Timestamp Errors in Business Process Event Logs -- Management -- Explorative Process Design Patterns -- Quo vadis, Business Process Maturity Model? Learning from the Past to Envision the Future -- A typological framework of process improvement project stakeholders -- BP-IT Alignment in SMEs: a Game-based Learning Approach to Increase Stakeholders' Maturity -- Understanding Quality in Declarative Process Modeling Through the Mental Models of Experts -- Adding Intelligent Robots to Business Processes: A Dilemma Analysis of Employees' Attitudes -- How to Keep RPA Maintainable? -- A Consolidated Framework for Implementing Robotic Process Automation Projects -- A Multi Perspective Framework for Enhanced Supply Chain Analytics -- Event Log Generation in a Health System: a Case Study.
• Sommario/riassunto: This book constitutes the proceedings of the 18th International Conference on Business Process Management, BPM 2020, held in Seville, Spain, in September 2020. The conference was held virtually due to the COVID-19 pandemic. The 27 full papers included in this volume were carefully reviewed and selected from 125 submissions. Two full keynote papers are also included. The papers are organized in topical sections named: foundations; engineering; and management.

Mass spectrometry in structural biology and biophysics : architecture, dynamics, and interaction of biomolecules / / Igor A. Kaltashov, Stephen J. Eyles

• Record Nr.: UNINA9911020041503321
• Autore: Kaltashov Igor A
• Pubbl/distr/stampa: Hoboken, N.J., : Wiley, c2012
• ISBN: 9786613620118; 9781280590283; 1280590289; 9781118232118; 1118232119; 9781118232125; 1118232127
• Edizione: [2nd ed.]
• Descrizione fisica: 1 online resource (312 p.)
• Collana: Wiley series on mass spectrometry
• Altri autori (Persone): EylesStephen J
• Disciplina: 610.28/4
• Soggetti: Mass spectrometry; Biophysics; Biomolecules - Spectra
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: MASS SPECTROMETRY IN STRUCTURAL BIOLOGY AND BIOPHYSICS: Architecture, Dynamics, and Interaction of Biomolecules; CONTENTS; Preface to the Second Edition; Preface to the First Edition; 1 General Overview of Basic Concepts in Molecular Biophysics; 1.1 Covalent Structure of Biopolymers; 1.2 Noncovalent Interactions and Higher Order Structure; 1.2.1 Electrostatic Interaction; 1.2.2 Hydrogen Bonding; 1.2.3 Steric Clashes and Allowed Conformations of the Peptide Backbone: Secondary Structure; 1.2.4 Solvent--Solute Interactions, Hydrophobic Effect, Side-Chain Packing, and Tertiary Structure; 1.2.5 Intermolecular Interactions and Association: Quaternary Structure1.3 The Protein Folding Problem; 1.3.1 What Is Protein Folding?; 1.3.2 Why Is Protein Folding So Important?; 1.3.3 What Is the Natively Folded Protein and How Do We Define a Protein Conformation?; ; 1.3.4 What Are Non-Native Protein Conformations?: Random Coils, Molten Globules, and Folding Intermediates; 1.3.5 Protein Folding Pathways; 1.4 Protein Energy Landscapes and the Folding Problem; 1.4.1 Protein Conformational Ensembles and Energy Landscapes: Enthalpic and Entropic Considerations; 1.4.2 Equilibrium and Kinetic Intermediates on the Energy Landscape1.5 Protein Dynamics and Function; 1.5.1 Limitations of the Structure--Function Paradigm; 1.5.2 Protein Dynamics under Native Conditions; 1.5.3 Is Well-Defined Structure Required for Functional Competence?; 1.5.4 Biomolecular Dynamics and Binding from The Energy Landscape Perspective; 1.5.5 Energy Landscapes Within a Broader Context of Nonlinear Dynamics: Information Flow and Fitness Landscapes; 1.6 Protein Higher Order Structure and Dynamics from A Biotechnology Perspective; References; 2 Overview of Traditional Experimental Arsenal to Study Biomolecular Structure and Dynamics2.1 X-Ray Crystallography; 2.1.1 Fundamentals; 2.1.2 Crystal Structures at Atomic and Ultrahigh Resolution; 2.1.3 Crystal Structures of Membrane Proteins; 2.1.4 Protein Dynamics and X-Ray Diffraction; 2.2 Solution Scattering Techniques; 2.2.1 Static and Dynamic Light Scattering; 2.2.2 Small-Angle X-Ray Scattering; 2.2.3 Cryo-Electron Microscopy; 2.2.4 Neutron Scattering; 2.3 NMR Spectroscopy; 2.3.1 Heteronuclear NMR; 2.3.2 Hydrogen Exchange by NMR; 2.4 Other Spectroscopic Techniques; 2.4.1 Cumulative Measurements of Higher Order Structure: Circular Dichroism2.4.2 Vibrational Spectroscopy; 2.4.3 Fluorescence: Monitoring Specific Dynamic Events; 2.5 Other Biophysical Methods to Study Macromolecular Interactions and Dynamics; 2.5.1 Calorimetric Methods; 2.5.2 Analytical Ultracentrifugation; 2.5.3 Surface Plasmon Resonance; 2.5.4 Size Exclusion Chromatography (Gel Filtration); 2.5.5 Electrophoresis; 2.5.6 Affinity Chromatography; References; 3 Overview of Biological Mass Spectrometry; 3.1 Basic Principles of Mass Spectrometry; 3.1.1 Stable Isotopes and Isotopic Distributions; 3.1.2 Macromolecular Mass: Terms and Definitions
• Sommario/riassunto: The definitive guide to mass spectrometry techniques in biology and biophysics The use of mass spectrometry (MS) to study the architecture and dynamics of proteins is increasingly common within the biophysical community, and Mass Spectrometry in Structural Biology and Biophysics: Architecture, Dynamics, and Interaction of Biomolecules, Second Edition provides readers with detailed, systematic coverage of the current state of the art. Offering an unrivalled overview of modern MS-based armamentarium that can be used to solve the most challenging problems in biophysics, structural biol