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1. |
Record Nr. |
UNISA996387623703316 |
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Titolo |
Songes and sonets written by the right honorable Lorde Henry Haward late Earle of Surrey, and others [[electronic resource]] |
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Pubbl/distr/stampa |
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[London], : Apud Richardum Tottell, 1574. Cum priuilegio |
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Descrizione fisica |
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Altri autori (Persone) |
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WyattThomas, Sir, <1503?-1542.> |
GrimaldNicholas <1519-1562.> |
TottelRichard <d. 1594.> |
SurreyHenry Howard, Earl of, <1517?-1547.> |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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The original edition contained 271 poems, of which 40 are by Surrey, 96 by Sir Thomas Wyatt, 40 by Nicholas Grimald (also sometimes identified as the editor), and 95 by various authors. This is a slightly different selection. |
Known as "Tottel's miscellany". |
In verse. |
Includes index. |
With a final colophon leaf. |
Running title reads: Songes and sonettes. |
Reproduction of the original in the Henry E. Huntington Library and Art Gallery. |
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Sommario/riassunto |
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2. |
Record Nr. |
UNINA9910791830603321 |
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Titolo |
Aggressive breast cancer [[electronic resource] /] / Regina H. DeFrina, editor |
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Pubbl/distr/stampa |
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New York, : Nova Science Publishers, c2010 |
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ISBN |
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Descrizione fisica |
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1 online resource (276 p.) |
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Collana |
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Cancer etiology, diagnosis and treatments series |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Breast - Cancer |
Breast - Diseases |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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""AGGRESSIVE BREAST CANCER ""; ""AGGRESSIVE BREAST CANCER ""; ""CONTENTS ""; ""PREFACE""; ""RESEARCH AND REVIEW ARTICLES""; ""THE HER2 ONCOGENE IN BREAST CANCER ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""HER PROTEIN RECEPTORS: SIGNAL TRANSDUCTION AND ONCOGENESIS ""; ""Intracellular Signaling Pathways ""; ""HER-Induced Cell Cycle Progression and Survival Pathways ""; ""OVER EXPRESSION OF HER2 AND THE PROGNOSIS OF INVASIVE BREAST CANCER ""; ""HER2 as A Prognostic Factor: Node-Positive Versus Node-Negative Disease""; ""HER Status and Lymphoid Infiltration "" |
""HER2 and Progression of Early Breast Cancer Lesions to Invasive Carcinomas""""Relationship Between HER2 and Estrogen Receptor Expression ""; ""HER2 ABNORMALITIES IN OTHER TYPES OF BREAST MALIGNANCIES ""; ""HER2 ABNORMALITIES IN OTHER TYPES OF BREAST MALIGNANCIES ""; ""Evaluating HER2 in Breast Tissue ""; ""HER2 TARGETED THERAPY IN BREAST CANCER ""; ""The Role of Trastuzumab in HER2 Overexpressing Breast Cancer ""; ""The Role of Pertuzumab in HER2 Overexpressing Breast Cancer ""; ""The Role of Trastuzumab-DM1 in HER2 Overexpressing Breast Cancer "" |
""Inhibiting Several HER Receptors: The Role of Lapatinib in HER2 Overexpressing Breast Cancer """"Circulating Serum HER2 Levels ""; ""PROPOSED RESISTANCE TO ANTI-HER2 THERAPIES ""; ""Altered Receptor-Antibody Interaction ""; ""Increased Signaling from other |
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Receptors of the HER Family ""; ""Increased Signaling from other Receptors Activating the MAPK and PI3K Pathways ""; ""Constitutive Activation of Downstream Effectors ""; ""HER2 OVEREXPRESSION AND CHEMOTHERAPY ""; ""Anthracyclines ""; ""Taxanes ""; ""HER2 OVEREXPRESSION AND HORMONAL THERAPY "" |
""CNS DISEASE IN HER2 OVEREXPRESSED BREAST CANCER """"CNS Metastases in Adjuvant Trials of Trastuzumab ""; ""Prognosis of CNS Metastases in HER2 Overexpressing Breast Cancer""; ""CONCLUSION ""; ""REFERENCES""; ""MULTI-DRUG RESISTANCE AS A PROBLEM CHALLENGING BREAST CANCER CHEMOTHERAPY ""; ""ABSTRACT ""; ""INTRODUCTION""; ""1) Non-Cellular MDR Mechanisms ""; ""2) Cellular MDR Mechanisms: ""; ""1. Changes in the intracellular accumulation and distribution of the drug ""; ""1a. Alteration of drug influx ""; ""1b. Alteration of drug efflux ""; ""NORMAL TISSUE DISTRIBUTION"" |
""PHYSIOLOGICAL FUNCTIONS OF P-GP """"PHARMACOLOGICAL FUNCTIONS OF P-GP ""; ""P-GP SUBSTRATES ""; ""2. Increase in Drug Detoxification ""; ""3. Alterations of Drug Targets ""; ""4. Increase in DNA Repair Mechanism ""; ""5. Changes in Key Genes Controlling Cell Proliferation ""; ""5a. Changes in genes responsible for cell cycle control ""; ""5b. Abrogation of apoptosis ""; ""6. Micro-Environmental Stress-Mediated Resistance of Solid Tumors ""; ""7. Cancer Cell Dormancy and Resistant Cancer Stem Cells ""; ""MODULATION OF MDR PHENOTYPE "" |
""I. Circumvention of Drug Resistance Induced by P-Gp Pump Protein "" |
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