1.

Record Nr.

UNISA996210237103316

Titolo

The Physical educator

Pubbl/distr/stampa

[Indianapolis, Ind.], : [Phi Epsilon Kappa Fraternity]

Urbana, IL, : Sagamore Publishing, LLC

ISSN

2160-1682

Descrizione fisica

1 online resource (volumes)

Disciplina

371.7305

Soggetti

Physical education and training

Physical Education and Training

Éducation physique

Periodicals.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Periodico

Note generali

Refereed/Peer-reviewed



2.

Record Nr.

UNINA9910972032203321

Autore

Nikanorova Marina

Titolo

Orphan Drugs in Epilepsy

Pubbl/distr/stampa

Montrouge, : JOHN LIBBEY EUROTEXT, 2014

ISBN

9782742012343

2742012346

Edizione

[1st ed.]

Descrizione fisica

1 online resource (90 p.)

Collana

Topics in Epilepsy ; ; v.4

Altri autori (Persone)

JohannessenS. I

GentonPierre

Disciplina

616.853

Soggetti

Epilepsy -- Treatment

Brain Diseases

Central Nervous System Agents

Drug Industry

Industry

Therapeutic Uses

Central Nervous System Diseases

Nervous System Diseases

Technology, Industry, and Agriculture

Pharmacologic Actions

Chemical Actions and Uses

Disease

Anticonvulsants

Epilepsy

Orphan Drug Production

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di contenuto

""Orphan Drugs in Epilepsy""; ""Contents""; ""Foreword""; ""Bromides""; ""Adrenocorticotropic hormone and corticosteroids""; ""Stiripentol""; ""Felbamate""; ""Rufinamide""

Sommario/riassunto

Over half of epilepsies start before the age of 20 years and nearly 25% of them are refractory. A tiny proportion of them are even labelled a rare illness (ie: one affecting less than 200,000 people in the United



States or less than 5 out of 10,000 people in the European Union). For these patients, two problems in their management arise: In children, seizures affect an immature brain and can impact its development. It is therefore essential to treat them so that brain development continues as normally as possible. The rarity of these syndromes does not encourage the pharmaceutical industry to invest in research. Therefore, there are few drugs available. However, a few target syndromes with a particularly unfavourable diagnosis. This work outlines 6 molecules in detail that are specifically used in epileptic encephalopathies. Every aspect of these molecules is discussed, including drug development, indication, efficacy, cost, etc. Drafted by international experts in the field of epileptology, it provides all the necessary information on orphan drugs and their clinical use.