Endothelial dysfunctions and vascular disease [[electronic resource] /] / edited by Raffaele De Caterina, Peter Libby ; foreword by Michael A. Gimbrone Jr

• Record Nr.: UNISA996208302403316
• Pubbl/distr/stampa: Malden, MA, : Blackwell Futura, 2007
• ISBN: 1-281-32011-0; 9786611320119; 0-470-98481-3; 0-470-98847-9; 0-470-99409-6
• Edizione: [1st ed.]
• Descrizione fisica: 1 online resource (432 p.)
• Altri autori (Persone): De CaterinaR. <1954->; LibbyPeter
• Disciplina: 616.1/3
• Soggetti: Blood-vessels - Pathophysiology; Vascular endothelium
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Endothelial Dysfunctions and Vascular Disease; Contents; Contributors; Preface; Foreword; Acknowledgments; Dedication; Part I: The basis of endothelial involvement in vascular diseases; 1 Endothelial functions and dysfunctions; 2 Endothelial activation and the initiation of atherosclerosis; 3 Mechanisms of plaque progression and complications; 4 Angiogenesis in cardiovascular disease; Part II: The endothelium and cardiovascular risk factors; 5 VLDL and atherosclerosis; 6 High-density lipoprotein and atheroprotection; 7 Advanced glycation endproducts and the accelerated atherosclerosis in diabetes8 Homocysteine and endothelial dysfunction; 9 Lipoprotein(a) and the artery wall; 10 Oxidative stress and vascular disease; 11 Infections and vascular disease; Part III: Diagnostic tools and markers of endothelial functions; 12 Endothelial vasodilatory dysfunction: basic concepts and practical implementation; 13 Endothelial vasodilatory dysfunction and risk factors in adults; 14 Endothelial vasodilatory dysfunction in early life; 15 Endothelial vasodilatory dysfunction in ; hypertension; 16 Vascular function and diabetes mellitus17 Dyslipidemia and endothelial dysfunction: pathophysiology and therapy; 18 Soluble adhesion molecules as in vivo biohumoral markers of vascular cell activation; Part IV: Endothelium-directed prevention and therapy; 19 Hormone replacement therapy and cardiovascular disease; 20 Anti-atherogenic effects of omega-3 fatty acids; 21 Treatment of endothelial dysfunction and atherosclerosis by cholesterol lowering; 22 Antioxidants and endothelial protection; 23 Angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor blockers to reverse endothelial dysfunction24 PPARs in atherosclerosis; 25 Stem cells in atherosclerosis and atherosclerosisrelated vascular disorders; 26 Endothelium-targeted gene and cell-based therapy for cardiovascular disease; Index
• Sommario/riassunto: Bridging the gap between the laboratory and the bedside, this timely volume illuminates the connection between endothelial dysfunction and vascular disease. This comprehensive survey of atherosclerotic disease begins with biology - incorporating the latest breakthroughs in the field - then elucidates risk factors and diagnostic tools and markers. A major section on endothelium-directed prevention and therapy shows you how to apply cutting-edge research to clinical care. Under the careful editorial guidance of Drs. De Caterina and Libby, the highly-regarded contributors address:- endothel