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Record Nr. |
UNISA990000839360203316 |
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Autore |
LIONS, Pierre Louis |
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Titolo |
Compressible models / Pierre-Louis Lions (2) |
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Pubbl/distr/stampa |
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Descrizione fisica |
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Disciplina |
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Collocazione |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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2. |
Record Nr. |
UNISA996205512603316 |
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Titolo |
Process analytical technology [[electronic resource] ] : spectroscopic tools and implementation strategies for the chemical and pharmaceutical industries / / edited by Katherine A. Bakeev |
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Pubbl/distr/stampa |
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Oxford, UK ; ; Ames, Iowa, : Blackwell Pub., 2005 |
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ISBN |
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1-280-74787-0 |
9786610747870 |
0-470-98845-2 |
1-4051-7319-X |
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Descrizione fisica |
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1 online resource (476 p.) |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Chemical process control - Industrial applications |
Chemistry, Technical |
Chemistry, Analytic - Technological innovations |
Chemistry, Analytic - Technique |
Spectrum analysis |
Pharmaceutical chemistry |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Process Analytical Technology : Spectroscopic Tools and Implementation Strategies for the Chemical and Pharmaceutical Industries; Contents; Contributors; Preface; List of Abbreviations; 1 Process Analytical Chemistry: Introduction and Historical Perspective; 1.1 Historical perspective; 1.2 Early instrument development; 1.3 Sampling systems; 1.4 Examples; References; 2 Implementation of Process Analytical Technologies; 2.1 Introduction to implementation of process analytical technologies (PATs) in the industrial setting; 2.1.1 Definition of process analytics |
2.1.2 Differences between process analyzers and laboratory analysis2.1.3 General industrial drivers for process analytics; 2.1.4 Types of applications (R&D vs. Manufacturing); 2.1.5 Organizational considerations; 2.2 Generalized process analytics work process; 2.2.1 Project identification and definition; 2.2.2 Analytical application development; 2.2.3 Design, specify and procure; 2.2.4 Implementation in production; 2.2.5 Routine operation; 2.2.6 Continuous improvement; 2.3 Differences between implementation in chemical and pharmaceutical industries; 2.3.1 Introduction; 2.3.2 Business model |
2.3.3 Technical differences2.3.4 Regulatory differences; 2.4 Conclusions; References; 3 Near-Infrared Spectroscopy for Process Analytical Chemistry: Theory, Technology and Implementation; 3.1 Introduction; 3.2 Theory of near-infrared spectroscopy; 3.2.1 Molecular vibrations; 3.2.2 Anharmonicity of the potential well; 3.2.3 Combination and overtone absorptions in the near-infrared; 3.2.4 Examples of useful near-infrared absorption bands; 3.3 Analyser technologies in the near-infrared; 3.3.1 The scanning grating monochromator; 3.3.2 Light sources and detectors for near-infrared analysers |
3.3.3 The polychromator photodiode-array analyser3.3.4 The acousto-optic tunable (AOTF) analyser; 3.3.5 Fourier transform near-infrared analysers; 3.4 The sampling interface; 3.4.1 Introduction; 3.4.2 Further discussion of sampling issues; 3.4.3 The use of fibre-optics; 3.5 Conclusion; Bibliography; 4 Infrared Spectroscopy for Process Analytical Applications; Abstract; 4.1 Introduction; 4.2 Basic IR spectroscopy; 4.3 Instrumentation design and technology; 4.4 Process IR instrumentation; 4.4.1 Commercially available IR instruments; 4.4.2 Important IR component technologies |
4.4.3 New technologies for IR components and instruments4.4.4 Requirements for process infrared analyzers; 4.4.5 Sample handling for IR process analyzers; 4.4.6 Issues for consideration in the implementation of process IR; 4.5 Applications of process IR analyzers; 4.6 Process IR analyzers: A review; 4.7 Trends and directions; References; 5 Process Raman Spectroscopy; 5.1 How Raman spectroscopy works; 5.2 When Raman spectroscopy works well and when it does not; 5.2.1 Advantages; 5.2.2 Disadvantages and risks; 5.3 What are the special design issues for process Raman instruments?; 5.3.1 Safety |
5.3.2 Laser wavelength selection |
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Sommario/riassunto |
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The use of real or near real time measurement of chemical production process parameters as the basis for achieving control or optimisation of a manufacturing process has wide application in the petrochemical, food and chemical industries. Process analytical chemistry (PAC), or |
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process analytical technology (PAT) as it has recently been called, is now being deployed in the pharmaceutical industry, where it is seen as a technology that can help companies to improve their conformity with manufacturing compliance regulations. The objective of this book is to provide a starting point |
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