1.

Record Nr.

UNISA996205506303316

Titolo

The pigmentary system [[electronic resource] ] : physiology and pathophysiology / / edited by James J. Nordlund ... [et al.]

Pubbl/distr/stampa

Malden, Mass., : Blackwell Pub., 2006

ISBN

1-280-74782-X

9786610747825

0-470-98398-1

0-470-98710-3

1-4051-5733-X

Edizione

[2nd ed.]

Descrizione fisica

1 online resource (1332 p.)

Classificazione

44.93

YF 4100

Altri autori (Persone)

NordlundJames J

Disciplina

612.7927

616.5

616.55

Soggetti

Pigmentation disorders

Melanocytes

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

The Pigmentary System: Physiology and Pathophysiology; Contents; Contributors; Foreword; Preface; Acknowledgments; The Physiology of the Pigmentary System; Historical and Comparative Perspectives of the Pigmentary System; 1 A History of the Science of Pigmentation; 2 Comparative Anatomy and Physiology of Pigment Cells in Nonmammalian Tissues; The Science of Pigmentation; 3 General Biology of Mammalian Pigmentation; 4 Extracutaneous Melanocytes; 5 Regulation of Melanoblast Migration and Differentiation; 6 Melanoblast Development and Associated Disorders; 7 Biogenesis of Melanosomes

8 Melanosome Traf.cking and Transfer9 Melanosome Processing in Keratinocytes; 10 The Regulation of Melanin Formation; 11 The Tyrosinase Gene Family; 12 Molecular Regulation of Melanin Formation: Melanosome Transporter Proteins; 13 Transcriptional Regulation of Melanocyte Function; 14 Enzymology of Melanin Formation; 15 Chemistry of Melanins; 16 The Physical Properties of Melanins; 17



Photobiology of Melanins; 18 Toxicological Aspects of Melanin and Melanogenesis; 19 Regulation of Pigment Type Switching by Agouti, Melanocortin Signaling, Attractin, and Mahoganoid

20 Human Pigmentation: Its Regulation by Ultraviolet Light and by Endocrine, Paracrine, and Autocrine Factors21 Paracrine Interactions of Melanocytes in Pigmentary Disorders; 22 Growth Factor Receptors and Signal Transduction Regulating the Proliferation and Differentiation of Melanocytes; 23 Aging and Senescence of Melanocytes; 24 The Genetics of Melanoma; 25 The Transformed Phenotype of Melanocytes; The Pathophysiology of Pigmentary Disorders; An Overview of Human Skin Color and its Disorders; 26 A More Precise Lexicon for Pigmentation, Pigmentary Disorders, and "Chromatic" Abnormalities

27 The Normal Color of Human Skin28 Mechanisms that Cause Abnormal Skin Color; Disorders of Hypopigmentation, Depigmentation and Hypochromia; 29 Genetic Hypomelanoses: Disorders Characterized by Congenital White Spotting-Piebaldism, Waardenburg Syndrome, and Related Genetic Disorders of Melanocyte Development-Clinical Aspects; 30 Genetic Hypomelanoses: Acquired Depigmentation; 31 Genetic Hypomelanoses: Generalized Hypopigmentation; 32 Genetic Hypomelanoses: Localized Hypopigmentation; 33 Genetic Hypomelanoses: Disorders Characterized by Hypopigmentation of Hair

34 Metabolic, Nutritional, and Endocrine Disorders35 Chemical, Pharmacologic, and Physical Agents Causing Hypomelanoses; 36 Infectious Hypomelanoses; 37 In.ammatory Hypomelanoses; 38 Hypomelanoses Associated with Melanocytic Neoplasia; 39 Miscellaneous Hypomelanoses: Depigmentation; 40 Miscellaneous Hypomelanoses: Hypopigmentation; 41 Miscellaneous Hypomelanoses: Extracutaneous Loss of Pigmentation; 42 Hypochromia without Hypomelanosis; Disorders of Hyperpigmentation and Hyperchromia; 43 Genetic Epidermal Syndromes: Disorders Characterized by Generalized Hyperpigmentation

44 Genetic Epidermal Syndromes: Disorders Characterized by Reticulated Hyperpigmentation

Sommario/riassunto

The most comprehensive and integrated book on pigmentation The Pigmentary System, Second Edition, gathers into one convenient, all-inclusive volume a wealth of information about the science of pigmentation and all the common and rare clinical disorders that affect skin color. The two parts, physiology (science) and pathophysiology (clinical disorders), are complementary and annotated so that those reading one part can easily refer to relevant sections in the other. For the clinician interested in common or rare pigment disorders or the principles of teaching about su