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1. |
Record Nr. |
UNISA990002432630203316 |
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Autore |
DUPONT, Jacques |
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Titolo |
Distruzione del tempio e fine del mondo : studi sul discorso di Marco 13 / Jacques Dupont |
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Pubbl/distr/stampa |
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Descrizione fisica |
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Collana |
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Disciplina |
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Collocazione |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Versione integrale dal francese di Carlo Danna |
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2. |
Record Nr. |
UNINA9911019559303321 |
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Autore |
Choi Seok-ki <1964-> |
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Titolo |
Synthetic multivalent molecules : concepts and biomedical applications / / Seok-ki Choi |
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Pubbl/distr/stampa |
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Hoboken, N.J., : Wiley, c2004 |
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ISBN |
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9786610541911 |
9781280541919 |
1280541911 |
9780471577706 |
0471577707 |
9780471578901 |
0471578908 |
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Descrizione fisica |
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1 online resource (446 p.) |
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Disciplina |
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Soggetti |
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Multivalent molecules - Synthesis |
Multivalent molecules - Design |
Multivalent molecules - Physiological effect |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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SYNTHETIC MULTIVALENT MOLECULES; CONTENTS; Preface; Notes for Organization and Classification; Abbreviations; 1 Introduction; 1.1 Nomenclature and Definitions; 1.1.1 Valency; 1.1.2 Linkers; 1.1.3 Scaffolds; 1.1.4 Ligand Density; 1.1.5 Homo- and Heterovalent Molecules; 1.2 Mechanistic Aspects of Multivalent Interaction; 1.2.1 Affinity Constant and Avidity; 1.2.2 Thermodynamics; 1.2.3 Kinetics; 1.2.4 Steric Effects; 1.3 Biological Roles of Multivalent Ligands; 2 Multivalent Molecules Applied to Viral Targets; 2.1 Influenza Virus; 2.1.1 Hemagglutinin; 2.1.1.1 Divalent Sialic Acid |
2.1.1.2 Tetravalent Sialoside2.1.1.3 Dendrimers Presenting Sialosides; 2.1.1.4 Sialic Acid Displayed in Liposomes; 2.1.1.5 Polymerized Liposome Presenting Sialic Acid; 2.1.1.6 Sialic Acid in Langmuir-Blodget Monolayers; 2.1.1.7 Sialic Acid Presented on Biopolymer Surfaces; 2.1.1.8 Poly(acrylamide) Presenting Sialosides; 2.1.1.9 Poly(acrylic acid) Presenting Sialosides; 2.1.1.10 Poly(acrylamide) Presenting C-Sialosides; 2.1.1.11 Postmodification of Activated Polymers; 2.1.1.12 Modes of Action of Polymeric Sialosides; 2.1.1.13 OPTCOL Assay; 2.1.1.14 ter-Poly(acrylic acid) Presenting Sialosides |
2.1.1.15 Poly(glutamic acid) Presenting Lysogangliosides2.1.1.16 Poly(glutamic acid) Bearing Sialic Acid-Containing Trisaccharides; 2.1.1.17 Poly(acrylamide) Bearing Sialic Acid Linked at the C(4) Position; 2.1.1.18 Poly(acrylamide) Tethering 9-O-Acetylsialosides; 2.1.1.19 Neoglycoprotein Displaying Sialic Acids; 2.1.1.20 Natural b-Inhibitors; 2.1.2 Neuraminidase; 2.1.2.1 Poly(glutamic acid) Presenting NA Inhibitors; 2.2 Human Immunodeficiency Virus; 2.2.1 HIV-1 Protease; 2.2.1.1 Divalent Terminal Peptides; 2.2.2 HIV-1 Reverse Transcriptase; 2.2.2.1 Heterodimers Composed of NRTI and NNRTI |
2.2.3 Glycoprotein 120 (gp120) on Viral Surfaces2.2.3.1 Neoglycoprotein-Displaying CD4 Peptide; 2.2.3.2 Galactosyl Ceramide Immobilized on Viral Surfaces; 2.2.3.3 Multivalent Anions; 2.2.3.4 Bivalent Antagonists of CXCR4; 2.2.4 Surface Carbohydrates on HIV; 2.2.4.1 Oligomannose Sugars Present on gp120; 2.2.4.2 Modes of CVN Recognition; 2.3 Rotavirus; 2.4 Polyoma Virus; 2.5 Picorna Virus; 2.6 Respiratory Syncytial Virus; 2.7 Dengue Virus; 2.8 Nucleic Acids of Viruses; 2.8.1 RNA-Protein Interactions; 2.8.1.1 Neomycin B Linked to Acridine; 2.8.1.2 Neamine Linked to Pyrene-Carboxylic Acid |
2.8.2 RNA-Enzyme Interactions2.8.3 Binders to the Minor Groove of Viral DNA; 2.8.3.1 Hairpin-Shaped Polyamide Dimers; 2.8.3.2 H-Shaped Polyamide Dimers; 2.8.3.3 Naturally Occurring Dimers; 2.9 Synthetic Multivalent Vaccines; 2.9.1 Peptide-Based Anti-influenza Vaccines; 2.9.2 Gp41-Based Anti-HIV Vaccine; 2.9.3 Peptide-Based Anti-FMDV Vaccines; 3 Multivalent Molecules Applied to Bacterial Targets; 3.1 Targets in Bacterial Cell Membranes; 3.1.1 D-Ala-D-Ala Peptide Precursors; 3.1.1.1 Mode of Action by Antibiotics of the Vancomycin Class; 3.1.1.2 Dimerization of Glycopeptide Antibiotics |
3.1.1.3 Di- and Trivalent Vancomycin |
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Sommario/riassunto |
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This book provides basic principles of multivalent interactions found in biological systems as well as an up-to-date and thorough coverage in design concepts, syntheses, and biological activities of multivalent molecules.* Contains practical examples of synthetic multivalent molecules in chemistry, biology, and medicine* Can be used as both a textbook for students and a reference book for libraries and |
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professionals* Includes detailed case studies* Fills a void in current literature through its devotion solely to multivalent molecules |
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