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1. |
Record Nr. |
UNINA9910785419903321 |
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Autore |
Carroon Jean <1952-> |
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Titolo |
Sustainable preservation [[electronic resource] ] : greening existing buildings / / Jean Carroon ; foreword by Richard Moe |
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Pubbl/distr/stampa |
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Hoboken, N.J., : Wiley, 2010 |
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ISBN |
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0-470-88215-8 |
1-283-02514-0 |
9786613025142 |
0-470-88213-1 |
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Descrizione fisica |
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1 online resource (435 p.) |
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Classificazione |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Sustainable architecture - United States |
Sustainable buildings - United States - Design and construction |
Historic preservation - United States |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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pt. I. Overview -- pt. II. Targeted resource conservation -- pt. III. Of special note. |
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Sommario/riassunto |
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"Sustainable Preservation takes a nuanced look at the hundreds of choices that adaptive reuse requires architects to make--from ingenious ways to redeploy existing structural elements to time-honored techniques for natural ventilation to creation of wetlands that restore a site's natural biological functions. In addition, Sustainable Preservation presents 50 case studies of projects--schools, houses, offices, stores, museums, and government buildings--that set new standards for holistic approaches to adaptive reuse and sustainability. The author covers design issues, from building location to lighting systems, renewable power options, stormwater handling, and building envelope protection and integrity. The book also reviews operational issues, including materials choices for low lifetime maintenance, green housekeeping, and indoor air quality."-- |
"The book contains case studies of key projects of a variety of types of buildings and provides key principles that architects and preservation |
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professionals can put into practice"-- |
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2. |
Record Nr. |
UNIORUON00039964 |
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Autore |
ARCE, Agustin |
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Titolo |
Documentos y textos para la historia de Tierra Santa y sus sanctuarios / Agustin Arce |
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Pubbl/distr/stampa |
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Jerusalem, : Franciscan Printing Press, 1970 |
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Descrizione fisica |
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Classificazione |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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3. |
Record Nr. |
UNINA9910830641003321 |
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Titolo |
Analysis of drug impurities [[electronic resource] /] / edited by Richard J. Smith and Michael L. Webb |
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Pubbl/distr/stampa |
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Oxford ; ; Ames, Iowa, : Blackwell, 2007 |
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ISBN |
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1-281-32024-2 |
9786611320249 |
0-470-98874-6 |
0-470-99422-3 |
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Descrizione fisica |
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1 online resource (290 p.) |
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Collana |
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Analytical chemistry series |
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Altri autori (Persone) |
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SmithRichard J |
WebbMichael L |
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Disciplina |
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Soggetti |
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Drugs - Analysis |
Materia medica |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Analysis of Drug Impurities; Contents; Preface; List of contributors; 1 Organic impurities in drug substance: origin, control, and measurement; 1.1 Introduction; 1.2 Origin of impurities; 1.2.1 Process impurities; 1.2.2 Degradation impurities; 1.2.3 Contamination impurities; 1.2.4 Other impurities; 1.3 Control of drug substance impurities; 1.3.1 Control of residual solvents; 1.3.2 Control of synthetic impurities; 1.3.3 Control of impurities in biological and botanical products; 1.3.4 Purification processes; 1.3.5 Control of impurities from packaging; 1.3.6 Control of contamination impurities |
1.3.7 Control of degradants on stability1.4 Measurement of drug substance impurities; 1.4.1 HPLC; 1.4.2 GC; 1.4.3 CE; 1.4.4 General considerations; 1.5 Conclusions; Disclaimer; References; 2 Organic impurities in drug products: origin, control and measurement; 2.1 Introduction; 2.2 Analytical methodology; 2.3 Drug-excipient compatibility experimental design; 2.4 Degradation mechanisms; 2.5 Excipients' role in drug product destabilisation; 2.6 Processing as a source of moisture; 2.7 Hydrolysis; 2.8 Oxidation; 2.9 Photolysis; 2.10 |
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Impact of processing on photostability |
2.11 Miscellaneous reactions2.12 Container-closure systems; References; 3 Stereochemical impurities; 3.1 Introduction; 3.2 Separation techniques: direct resolution; 3.2.1 HPLC using CSPs; 3.2.2 HPLC using chiral mobile-phase additives; 3.2.3 Capillary electrophoresis using chiral selectors; 3.2.4 Supercritical fluid chromatography using chiral stationary phases; 3.2.5 Gas chromatography using chiral stationary phases; 3.3 Separation techniques: indirect resolution; 3.4 Non-separation techniques; 3.4.1 Chiroptical spectroscopy; 3.4.2 Nuclear magnetic resonance spectroscopy; 3.5 Conclusions |
AcknowledgementsReferences; 4 Low-level measurement of potent toxins; 4.1 Introduction; 4.2 Classes of genotoxic impurity; 4.2.1 Alkylating agents; 4.2.2 Reactive amines; 4.2.3 Fused tricyclics; 4.2.4 Substituted purines and pyrimidines; 4.2.5 Hydroperoxides; 4.3 The analytical challenge of genetic; 4.4 Gas chromatography; 4.4.1 Sample introduction techniques; 4.4.2 Detectors; 4.5 High-performance liquid chromatography; 4.5.1 Separation modes; 4.5.2 Detection techniques; 4.6 Supercritical fluid chromatography; 4.7 Thin-layer chromatography; 4.8 Sample pre-concentration |
4.8.1 Liquid-liquid extraction4.8.2 Solid-phase extraction; 4.8.3 Solid-phase microextraction; 4.8.4 Liquid-phase microextraction; 4.9 Other techniques; 4.9.1 Electrochemical measurements; 4.9.2 Derivatisation methods; 4.10 Adapting analytical methods from fields beyond pharmaceuticalsimpurities analysis; 4.10.1 Antineoplastic agents; 4.10.2 Other fields; 4.11 Validation of trace analytical methods; 4.11.1 Sensitivity; 4.11.2 Specificity; 4.11.3 Accuracy; 4.11.4 Solution stability; 4.11.5 Linearity and precision; 4.12 Conclusions; References; 5 A systematic approach to impurity identification |
5.1 Introduction |
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Sommario/riassunto |
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A key component of the overall quality of a pharmaceutical is control of impurities, as their presence, even in small amounts, may affect drug safety and efficacy. The identification and quantification of impurities to acceptable standards presents a significant challenge to the analytical chemist. Analytical science is developing rapidly and provides increasing opportunity to identify the structure, and therefore the origin and safety implications of these impurities, and the challenges of their measurement drives the development of modern quantitative methods.Written for both practic |
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