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Record Nr. |
UNINA9911104374503321 |
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Titolo |
Extracellular matrix : pathobiology and signaling / / edited by Nikos K. Karamanos |
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Pubbl/distr/stampa |
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Berlin, : Walter de Gruyter, c2012 |
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ISBN |
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9786613940193 |
9781283627740 |
1283627744 |
9783110258776 |
3110258773 |
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Edizione |
[1st ed.] |
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Descrizione fisica |
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1 online resource (940 p.) |
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Classificazione |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Extracellular matrix |
Cellular signal transduction |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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An introduction to the extracellular matrix molecules and their importance in pathobiology and signaling / Achilleas Theocharis ... [et al.] -- Insights into the function of glycans / Paraskevi Heldin -- Proteoglycans : structure, pathobiology, and signaling / Liliana Schaefer -- ECM cell surface receptors / Donald Gullberg -- Extracellular proteinases / Jan-Olof Winberg -- Collagen : not just mechanics, for the high degree of connectivity grounded on the apparently simple triple helix / Ruggero Tenni -- Emerging aspects in extracellular matrix pathobiology / Achilleas Theocharis -- Targeting tumor microenvironment at the ECM level / Nikos K. Karamanos. |
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Sommario/riassunto |
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Over the last decades cell biology and biological chemistry have increasingly turned their attention to the space between cells and revealed an elaborate network of macromolecules essential for structural support, cell adhesion and signaling. This comprehensive handbook of the extracellular matrix will give an overview of the current state of knowledge of matrix components (structure and function), their role in heath and disease (matrix pathobiology) and new aspects related to pharmacological targeting.It will provide an |
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introduction to the extracellular matrix and detailed sections and chapters on: Importance of extracellular matrix in health and disease Matrix proteoglycans (aggrecan, versican, perlecan, SLRPs, syndecans, glypicans, serglycin) Matrix proteinases (remodeling, would healing, regulatory roles in health and disease, metalloproteinases, cystein proteases, plasmin and plasminogen activator system) Glycobiology (hyaluronan and sulfated glycosaminoglycans in cancer, inflammation and metabolic control) Collagens (supramolecular assembly, proteins binding collagen, scaffolds, bacterial and mutated collagens, procollagen proteinases) Cell surface receptors (integrins, syndecans, mechanical strain and TGFb, CD44 and DDR). Biotechnological and pharmacological outlook (matrix regulation by growth factors, hyaluronidases, pathobiology, disease targeting, delivery systems, EMT and proteomics). "The book Extracellular Matrix: Pathobiology and Signaling provides a comprehensive and up to date collection of very relevant topics for understanding the various facets of extracellular matrix and its interactions with cells in normal tissue as well as in disease. It represents the current front-line and will serve as a reference for extracellular matrix and posttranslational modifications." Dick Heinegård, Department of Clinical Sciences Lund, Section Rheumatology, Lund University, Sweden |
Over the last decades cell biology and biological chemistry have increasingly turned their attention to the space between cells and revealed an elaborate network of macromolecules essential for structural support, cell migration, adhesion and signaling. This comprehensive handbook of the extracellular matrix is organized into seven thematic sections, giving an overview of the current state of knowledge of matrix components (structure and function), their roles in health and disease (matrix pathobiology) as well as new concepts of pharmacological targeting. |
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2. |
Record Nr. |
UNINA9911114171103321 |
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Autore |
Nguyen Ngoc Thanh |
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Titolo |
The 14th Conference on Information Technology and its Applications : Proceedings of the International Conference CITA 2025 / / edited by Ngoc Thanh Nguyen, Cong-Phap Huynh, Thanh Thuy Nguyen, Nhien-An Le-Khac, Sopheap Seng, Quang-Vu Nguyen |
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Pubbl/distr/stampa |
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Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2026 |
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ISBN |
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3-032-00972-3 |
9783032009722 |
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Edizione |
[1st ed. 2026.] |
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Descrizione fisica |
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1 online resource (1364 pages) |
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Collana |
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Lecture Notes in Networks and Systems, , 2367-3389 ; ; 1581 |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Engineering - Data processing |
Computational intelligence |
Artificial intelligence |
Data Engineering |
Computational Intelligence |
Artificial Intelligence |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Factors Affecting The Adoption Intention Of Using Fintech Payments -- The Role of Emotional Experience in Student Engagement on E-Learning Platforms An Extended Technology Acceptance Model -- An effective method for fall detection based on YOLO in IoT Applications -- Enhancing Test Smell Prediction with Stacking Ensemble Learning -- An Enhanced GSC Beamformer’s Evaluation Based on Post Filtering -- A 2 index Stage based Formulation and a Construct, Merge, Solve & Adapt Algorithm for the Flying Sidekick Traveling Salesman Problem -- Fine-tuning Multilingual Khmer Neural Machine Translation -- ViSWAP: Vietnamese Voice Conversion System with Diffusion Model -- Compact Design of a Normal-Mode Helical Antenna for Wireless Temperature Monitoring -- Human Fall Detection and Indoor Localization Using WiFi Sensing Approach -- An Increased Robustness of Speech Enhancement on Dual Microphone System -- Time-domain Target Speaker Extraction with Parallel Intra and Inter-framework -- NTDREG: An Effective |
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Regression Unit Testing Method for Java Projects -- A Comparative Analysis of Models Based on Convolutional Neural Network for WiFi Fingerprinting -- Accelerating Software Development Cycle with a Multi Agent Generative AI Approach A Case Study with OpenAI’s GPT -- A Fusion Model of Neural Attention Mechanism and Matrix Factorization for Sequential Recommendation Systems -- An Explainable Biased Matrix Factorization Approach for Recommendation Systems -- Portfolio optimization with return prediction on Vietnam stock market -- Exploring Dynamic Parameters for Vietnamese Gender Independent ASR -- Whisper based Cross Lingual Phoneme Recognition between Vietnamese and English -- A Comparative Study on Domain and Content Based Approaches for Abusive Website Detection -- A Comprehensive Survey on Software Effort Estimation using Machine Learning and Optimization Algorithms -- Auto-ARM An Autonomous Adaptive Mask Refinement Mechanism for Enhancing Naturalness in Virtual Try On Models -- A Hybrid Deep Learning Approach to Stress Detection Integrating CNN LSTM with Reinforcement Learning and Active Learning -- STUBLIB4UT A Stub Generation Method For Library Functions In Unit Testing Java Projects -- Thriving Amidst Technostress The Impact of Technostress Creators on Task Performance and Job Satisfaction via Burnout and Technostress Inhibitors Evidence from Vietnam -- A Hybrid Approach to Fault Localization Integrating LLMs with IR-based Methods -- BOLIMES Boruta–LIME optiMized fEature Selection for Gene Expression Classification -- RACNN Residual Attention Convolutional Neural Network for Near-Field Channel Estimation in 6G Wireless Communications. |
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Sommario/riassunto |
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This book presents selected papers from the 14th Conference on Information Technology and its Applications (CITA) which will take place on July 14–15, 2025 in Phnom Penh, Cambodia on July 14–15, 2025. The 14th CITA (CITA 2025) will be co-organized by Vietnam-Korea University of Information and Communication Technology (Vietnam), Cambodia Academy of Digital Technology (Cambodia) and King Mongkut's University of Technology North Bangkok (Thailand). The conference also is supported and accompanied by the research and training institutions belonging to the ASEAN Consortium for Innovation and Research (ACIR) as well as the Vietnam ICT Association of Faculties-Institutes-Schools-Universities (FISU Vietnam), Wroclaw University of Science and Technology (Poland), University College Dublin (Ireland), Springer and SMCS (IEEE). Conference on Information Technology and its Applications (CITA) initiated in 2012 is an annual international scientific conference on information technology and its applications. |
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