1.

Record Nr.

UNINA9911093555103321

Titolo

Ataxia : causes, symptoms and treatment / / Sung Hoi Hong, editor

Pubbl/distr/stampa

New York, : Nova Science Publishers, c2012

ISBN

1-61942-869-5

Edizione

[1st ed.]

Descrizione fisica

1 online resource (213 p.)

Collana

Neuroscience research progress

Altri autori (Persone)

HongSung Hoi

Soggetti

Ataxia

Movement disorders

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

""ATAXIA ""; ""ATAXIA ""; ""CONTENTS ""; ""PREFACE ""; ""ROLE OF THE ATAXIA TELANGIECTASIA MUTATED PROTEIN IN STRESS-INDUCED  PREMATURE SENESCENCE ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""ATM ACTIVATION ""; ""ATM SUBSTRATES ""; ""P53 STRUCTURE, ACTIVATION AND FUNCTION ""; ""ROLES OF ATM AND P53 IN DNA REPAIR""; ""MULTIPLE FUNCTIONS OF P21 IN THE ATM NETWORK ""; ""SEQUENTIAL WAVES OF P53 ACTIVATION BY DNA DAMAGE ""; ""ATM-DEPENDENT SENESCENCE ""; ""ATM-INDEPENDENT SENESCENCE ""; ""ROLE OF ATM IN PREVENTING ESCAPE FROM SIPS: A NOVEL TUMOR SUPPRESSOR FUNCTION BEYOND P53? ""

""POTENTIAL THERAPEUTIC APPROACHES FOR THE  TREATMENT OF AT """"CONCLUSION""; ""ACKNOWLEDGMENTS ""; ""REFERENCES""; ""ATAXIA TELANGIECTASIA: MOLECULAR BASIS, DIAGNOSIS AND TREATMENT ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""CLINICAL FEATURES OF A-T ""; ""Neurological Phenotype and Cutaneous Manifestations ""; ""Immunodeficiency and Pulmonary Complications ""; ""Predisposition to Cancer and Chromosomal Instability""; ""Endocrine Dysfunction ""; ""PATHOGENESIS AND MOLECULAR DEFECT ""; ""ATM and Neurodegeneration""; ""ATM and Oxidative Stress ""; ""DIAGNOSIS AND TREATMENT ""; ""CONCLUSION ""

""REFERENCES """"THE NEUROBIOLOGY OF EPISODIC ATAXIA TYPE 1, A SHAKER-LIKE K+ CHANNEL DISORDER ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""STRUCTURE AND FUNCTION OF SHAKER-LIKE K+ CHANNELS ""; ""PHYSIOLOGICAL ROLE OF KV CHANNELS "";



""Hippocampus ""; ""Cerebellum ""; ""Sciatic Nerve ""; ""BIOTECHNOLOGY FOR STUDYING ION CHANNELS ""; ""EPISODIC ATAXIA TYPE 1: ""; ""Clinical Findings ""; ""Genetic Causes ""; ""Molecular Pathogenetic Mechanisms Underlying EA1""; ""Animal Models of EA1""; ""Treatment of EA1 ""; ""BRIEF OVERVIEW OF RELATED ATAXIA DISORDERS ""; ""CONCLUSION ""; ""ACKNOWLEDGMENTS ""

""REFERENCES """"MITOCHONDRIAL ATAXIAS ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""ATAXIA IN MITOCHONDRIAL DISORDERS ""; ""MtDNA Point Mutations ""; ""MtDNA Sporadic Rearrangements ""; ""Infantile Onset Spinocerebellar Ataxia ""; ""POLG1-Related Diseases ""; ""OPA1-Related Diseases ""; ""Coenzyme Q10 Deficiency ""; ""FRIEDREICH ATAXIA ""; ""Mitochondrial Therapies for Friedreich Ataxia ""; ""MITOCHONDRIA AND OTHER GENETIC ATAXIAS ""; ""Dominant Spino-Cerebellar Ataxias ""; ""X-Linked Ataxias ""; ""CONCLUSION ""; ""REFERENCES ""

""EPIDEMIC SEASONAL ATAXIC SYNDROME: EPIDEMIOLOGY, CLINICAL PRESENTATION, ETIOLOGICAL MECHANISMS AND THERAPY   """"ABSTRACT ""; ""INTRODUCTION ""; ""ETIOLOGY ""; ""Viral Hypothesis ""; ""Toxins in Food""; ""Hypothesis of Thiamine Deficiency ""; ""CLINICAL PRESENTATION OF SAS IS COMPATIBLE WITH WERNICKEâ€?S ENCEPHALOPATHY ""; ""MECHANISM OF THIAMINE DEFICIENCY  IN SEASONAL ATAXIC SYNDROME ""; ""THERAPY AND CONTROL OF SAS ""; ""REFERENCES ""; ""CLINICAL AND GENETIC ASPECTS OF RECESSIVE ATAXIAS ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""THE DEGENERATIVE ATAXIAS ""; ""Friedreichâ€?s Ataxia ""

""Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS) ""

Sommario/riassunto

Ataxia is a neurological sign and symptom characterised by lack of co-ordination of muscle movement that is due to dysfunction of the parts of the nervous system, such as motor control of the cerebellum. Although the cause of the dysfunction varies from mutations in channels for potassium and/or calcium to progressive degeneration of cerebellar tissue-specific neurons, the neurological signs and symptoms of ataxia are similar. The treatment of ataxia and its effectiveness depend on the underlying cause, and it could be managed by pharmacological treatments and through physical therapy and occupational therapy. The treatment may ameliorate the signs of ataxia, but it is not likely to eliminate them entirely. In this book, the authors present current research in the study of the causes, symptoms and treatments on ataxia.



2.

Record Nr.

UNINA9911098422303321

Autore

Kartinyeri Doris <1945->

Titolo

Kick the tin / / by Doris E. Kartinyeri

Pubbl/distr/stampa

North Melbourne, : Spinifex Press, 2000

ISBN

1-74219-432-X

1-74219-106-1

1-74219-104-5

Edizione

[1st ed.]

Descrizione fisica

1 online resource (162 p.)

Disciplina

305.89915

994.04092

994.05092

Soggetti

Children, Aboriginal Australian - Institutional care - Australia - South Australia

Aboriginal Australians - Australia - South Australia

History - Biographies - Indigenous - Autobiographies

Child welfare - Child / parent separation - Stolen generations

Government policy - State and territory - South Australia

Eden Hills (Adelaide SA SI54-09)

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di contenuto

BOOK COVER; TITLE; COPYRIGHT; CONTENTS; DEDICATION; ACKNOWLEDGMENTS; PREFACE; FOREWORD; GLOSSARY; STOLEN; PROTECTION; THE BEGINNING OF GRIEF; SHUNTED ABOUT; NEED TO BELONG; JOURNEYS FROM REALITY; MY GUIDING HANDS; FINDING MY VOICE; NGARRINDJERI MIMINI

Sommario/riassunto

When Doris Kartinyeri was a month old, her mother died. The family gathered to mourn their loss and welcome the new baby home. But Doris never arrived to live with her family ? she was stolen from the hospital and placed in Colebrook Home, where she stayed for the next fourteen years.The legacy of being a member of the Stolen Generations continued for Doris as she was placed in white homes as a virtual slave, struggled through relationships and suffered with anxiety and mental illness.This is a life that has been kicked around. It is the compelling



and sometimes witty memoir of a cou