1.

Record Nr.

UNINA9910983355503321

Titolo

Genetic Models of Down Syndrome / / edited by Bing Ye, Roger Reeves

Pubbl/distr/stampa

Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2025

ISBN

9783031786112

3031786114

Edizione

[1st ed. 2025.]

Descrizione fisica

1 online resource (VII, 274 p. 33 illus., 30 illus. in color.)

Disciplina

616.042072

Soggetti

Genetics - Research

Genetics

Developmental biology

Genetics Research

Developmental Biology and Stem Cells

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

Chapter 1: Introduction -- Chapter 2 : Rodent Models of Down Syndrome I: Mouse & Rat -- Chapter 3: Rodent Models of Down Syndrome II: Mouse -- Chapter 4: Rodent Models of Down Syndrome III: Mouse -- Chapter 5: Modeling Down Syndrome in C. elegans -- Chapter 6: Modeling Down Syndrome in Drosophila -- Chapter 7: Zebrafish Models of Down Syndrome -- Chapter 8: Using Human Brain organoids to Study Down Syndrome -- Chapter 9: Cellular Models: Stem Cells and other Cellular Models.-Chapter 10: Conclusions and Perspectives.

Sommario/riassunto

Down syndrome is a textbook example of a chromosomal disorder and is common, occurring in 1 in 700 live births in the US. While there are many books previously published on the genetics of Down syndrome, and many studies in diverse species, this is the first book of its kind on the research models for Down syndrome that covers animal models. This book offers an in-depth introduction and discussion of the genetic models of down syndrome across diverse species, including rodents, zebrafish, drosophila, and human organoids. Authors use a cross-cutting approach to compare the strengths and weaknesses of each model system, explore how to use model organisms to study human



diseases, and capture the status of the field. This book is a useful resource for biomedical researchers and students interested in using model systems to study Down syndrome and learn about Down syndrome and other chromosomal disorders.

2.

Record Nr.

UNINA9911055726403321

Titolo

BSAVA textbook of veterinary nursing / editors: Barbara Cooper, Elizabeth Mullineaux, Lynn Turner

Pubbl/distr/stampa

Quedgeley, Gloucester, : British small animal veterinary association, 2020

ISBN

9781910443392

Edizione

[6. ed]

Descrizione fisica

xiii, 946 p. : ill. ; 30 cm

Disciplina

636.089073

Locazione

FMVBC

Collocazione

636.089073 COO1

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia