1.

Record Nr.

UNINA9911031631803321

Autore

Rezaei Nima

Titolo

Cancerous Cells : Immunobiology of Tumors and Metastasis / / edited by Nima Rezaei

Pubbl/distr/stampa

Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2025

ISBN

3-032-00759-3

Edizione

[1st ed. 2025.]

Descrizione fisica

1 online resource (1572 pages)

Collana

Handbook of Cancer and Immunology, , 3091-3675 ; ; 2

Disciplina

616.994079

Soggetti

Cancer

Immunology

Immunotherapy

Tumors - Immunological aspects

Cancer - Treatment

Cancer Biology

Tumour Immunology

Cancer Therapy

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

Introduction on Cancerous Cells and Metastasis -- Cancer Antigens Sources, Generation, and Presentation -- Cancer Stem Cells: Roles in Cancer Etiology -- Intercellular Communication in Cancer -- Intra-Tumor Cell Heterogeneity Different Immune Responses for Different Cells -- Crosstalk Between Cancer Associated Fibroblasts and Immune Cells -- Role of Extracellular Vesicles in Cancer Pathogenesis -- Apoptosis in Cancer -- Gut-Brain Axis.-Mucosal Exposome and Intestinal Carcinogenesis.

Sommario/riassunto

The rapid flow of studies in the field of cancer and immunology during the last decades has increased our understanding of the interactions between the immune system and cancerous cells. In particular, it has been well-known that such interactions result in the induction of epigenetic changes in cancerous cells and the selection of less immunogenic clones as well as alterations in immune responses. Understanding the crosstalk between nascent transformed cells and cells of the immune system has led to the development of



combinatorial immunotherapeutic strategies to combat cancer. The Handbook of Cancer and Immunology offers a comprehensive and up-to-date review of cancer immunology and immunotherapy, emphasizing key findings and clinically relevant data. This reference work is an essential resource for researchers, students, academics, and clinicians committed to advancing knowledge, diagnostics, and treatments in this vital field.