1.

Record Nr.

UNINA9911020228903321

Autore

Machin David <1939->

Titolo

Design of studies for medical research / / David Machlin, Michael J. Campbell

Pubbl/distr/stampa

Hoboken, NJ, : Wiley, c2005

ISBN

9786610275663

9781280275661

1280275669

9780470012994

0470012994

9780470012987

0470012986

Descrizione fisica

1 online resource (286 p.)

Altri autori (Persone)

CampbellMichael J

Disciplina

610/.72

Soggetti

Medicine - Research - Methodology

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references (p. [246]-254) and index.

Nota di contenuto

Design of Studies for Medical Research; Contents; Preface; Chapter 1 What is Evidence?; Chapter 2 Measurement, Forms and Questionnaires; Chapter 3 Principles of Study Size Calculation; Chapter 4 Randomisation; Chapter 5 Cross-sectional and Longitudinal Studies; Chapter 6 Surveys, Cohort and Case-Control Studies; Chapter 7 Clinical Trials - General Issues; Chapter 8 Early Clinical Trials; Chapter 9 Phase III Trials; Chapter 10 Diagnosis; Chapter 11 Prognostic Factor Studies; References; Tables; Index

Sommario/riassunto

The same careful rigour imposed on the design of phase III randomised controlled trials is not always applied to medical research in other areas such as trials conducted at earlier stages of drug development.  With the emphasis that is now placed on evidence-based medicine, such care and rigour will inevitably impact on these areas with increasing attention turned to the quality of design.  This title describes what principles can be used to structure research effectively allowing for the required degree of accuracy. Written by two best selling authors, this book includes many examples f