1.

Record Nr.

UNINA9911020187803321

Titolo

Protein misfolding diseases : current and emerging principles and therapies / / edited by Marina Ramirez-Alvarado, Jeffery W. Kelly, Christopher M. Dobson

Pubbl/distr/stampa

Hoboken, N.J., : Wiley, c2010

ISBN

9786612653551

9781118031810

1118031814

9781282653559

1282653555

9780470572702

0470572701

9780470572696

0470572698

Descrizione fisica

1 online resource (1102 p.)

Collana

Wiley series on protein and peptide science

Altri autori (Persone)

Ramirez-AlvaradoMarina

KellyJeffery W

DobsonC. M (Christopher M.)

Disciplina

616.3/995

Soggetti

Proteins - Metabolism - Disorders

Protein folding

Amyloidosis

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

PROTEIN MISFOLDING DISEASES; CONTENTS; CONTRIBUTORS; FOREWORD; PREFACE; ACKNOWLEDGMENTS; INTRODUCTION TO THE WILEY SERIES ON PROTEIN AND PEPTIDE SCIENCE; PART I PRINCIPLES OF PROTEIN MISFOLDING; PART II PROTEIN MISFOLDING DISEASE: GAIN-OF-FUNCTION AND LOSS-OF-FUNCTION DISEASES; PART III ROLE OF ACCESSORY MOLECULES AND RISK FACTORS; PART IV MEDICAL ASPECTS OF DISEASE: DIAGNOSIS AND CURRENT THERAPIES; PART V APPROACHES FOR NEW AND EMERGING THERAPIES; INDEX

Sommario/riassunto

An increasingly aging population will add to the number of individuals



suffering from amyloid. Protein Misfolding Diseases provides a systematic overview of the current and emerging therapies for these types of protein misfolding diseases, including Alzheimer's, Parkinson's, and Mad Cow. The book emphasizes therapeutics in an amyloid disease context to help students, faculty, scientific researchers, and doctors working with protein misfolding diseases bridge the gap between basic science and pharmaceutical applications to protein misfolding disease.