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1. |
Record Nr. |
UNISA990000735240203316 |
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Titolo |
Introduzione all'economia delle amministrazioni pubbliche / Elio Borgonovi... et al. ; a cura di Elio Borgonovi |
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Pubbl/distr/stampa |
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Milano : A.Giuffré, 1984 |
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ISBN |
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Descrizione fisica |
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Collana |
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Università "L. Bocconi", Dipartimenti di economia aziendale ; 71 |
Economia della pubblica amministrazione ; 2 |
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Disciplina |
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Collocazione |
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XXX.B. Coll. 193/ 43 (X 32 XXVI 2) |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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2. |
Record Nr. |
UNISA996577959703316 |
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Titolo |
ISO/IEC 8802-11, Second edition : 2005/Amendment 6 2006 : IEEE STD 802.11i-2004 (Amendment to IEEE Std 802.11-1999) : ISO/IEC International Standard - Information Technology Telecommunications and Information Exchange Between Systems Local and Metropolitan / / Institute of Electrical and Electronics Engineers |
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Pubbl/distr/stampa |
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[Place of publication not identified] : , : IEEE, , 2004 |
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ISBN |
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Descrizione fisica |
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1 online resource (185 pages) |
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Disciplina |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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3. |
Record Nr. |
UNINA9911020108703321 |
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Titolo |
Prodrugs and targeted delivery : towards better ADME properties / / edited by Jarkko Rautio |
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Pubbl/distr/stampa |
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Weinheim, Germany, : Wiley-VCH, 2011 |
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ISBN |
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9786613140579 |
9781283140577 |
1283140578 |
9783527633180 |
3527633189 |
9783527633166 |
3527633162 |
9783527633173 |
3527633170 |
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Descrizione fisica |
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1 online resource (522 p.) |
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Collana |
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Methods and principles in medicinal chemistry ; ; v. 47 |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Prodrugs and Targeted Delivery: Towards Better ADME Properties; Contents; List of Contributors; Preface; A Personal Foreword; Part One: Prodrug Design and Intellectual Property; 1 Prodrug Strategies in Drug Design; 2 The Molecular Design of Prodrugs by Functional Group; 3 Intellectual Property Primer on Pharmaceutical Patents with a Special Emphasis on Prodrugs and Metabolites; Part Two: Prodrugs Addressing ADMET Issues; 4 Increasing Lipophilicity for Oral Drug Delivery; 5 Modulating Solubility Through Prodrugs for Oral and IV Drug Delivery |
6 Prodrugs Designed to Target Transporters for Oral Drug Delivery7 Topical and Transdermal Delivery Using Prodrugs: Mechanism of Enhancement; 8 Ocular Delivery Using Prodrugs; 9 Reducing Presystemic Drug Metabolism; 10 Enzyme-Activated Prodrug Strategies for Site-Selective Drug Delivery; 11 Prodrug Approaches for Central Nervous System Delivery; 12 Directed Enzyme Prodrug Therapies; Part |
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Three: Codrugs and Soft Drugs; 13 Improving the Use of Drug Combinations Through the Codrug Approach; 14 Soft Drugs; Part Four: Preclinical and Clinical Consideration for Prodrugs |
15 Pharmacokinetic and Biopharmaceutical Considerations in Prodrug Discovery and Development16 The Impact of Pharmacogenetics on the Clinical Outcomes of Prodrugs; Index |
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Sommario/riassunto |
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This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning at the early stages of the development process, as well as discussing organ- and site-selective prodrugs. Every company employing medicinal chemists will be interested in this practice-oriented overview of a key strategy in modern drug discovery and development. |
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