1.

Record Nr.

UNINA9911020015903321

Titolo

Statistical diagnostics for cancer : analyzing high-dimensional data / / edited by Frank Emmert-Streib and Matthias Dehmer

Pubbl/distr/stampa

Weinheim, : Wiley-Blackwell, 2013

ISBN

9783527665471

3527665471

9781299158511

129915851X

9783527665440

3527665447

9783527665457

3527665455

Descrizione fisica

1 online resource (xx, 292 pages) : illustrations (some color)

Collana

Quantitative and network biology ; ; v. 3

Altri autori (Persone)

Emmert-StreibFrank

DehmerMatthias <1968->

Disciplina

616.994075

Soggetti

Cancer - Diagnosis

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

pt. 1. General overview -- pt. 2. Bayesian methods -- pt. 3. Network-based approaches -- pt. 4. Phenotype influence of DNA copy number aberrations.

Sommario/riassunto

This ready reference discusses different methods for statistically analyzing and validating data created with high-throughput methods. As opposed to other titles, this book focusses on systems approaches, meaning that no single gene or protein forms the basis of the analysis but rather a more or less complex biological network. From a methodological point of view, the well balanced contributions describe a variety of modern supervised and unsupervised statistical methods applied to various large-scale datasets from genomics and genetics experiments. Furthermore, since the availability of suffi