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Record Nr. |
UNINA9910384258903321 |
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Titolo |
Brain science advances |
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Pubbl/distr/stampa |
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London : , : SAGE Publications |
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Beijing : , : Tsinghua University Press, , 2018- |
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ISSN |
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Disciplina |
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Soggetti |
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Neurosciences |
Medical innovations |
Periodicals. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Periodico |
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Note generali |
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"Brain Science Advances (BSA) is an international, peer-reviewed, open access journal which publishes original research articles, review articles and case reports on all aspects of brain sciences with a focus on molecular and cellular neuroscience, clinical neuroscience, and neural engineering. It is published quarterly by Tsinghua University Press and SAGE Publishing"--Journal description. |
Refereed/Peer-reviewed |
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2. |
Record Nr. |
UNINA9911020007303321 |
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Autore |
Colombo Paolo <1944-> |
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Titolo |
Inhalation drug delivery : techniques and products / / Paolo Colombo, Daniela Traini, Francesca Buttini |
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Pubbl/distr/stampa |
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Chichester, West Sussex, U.K., : Wiley-Blackwell, 2013 |
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ISBN |
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9781118397145 |
1118397142 |
9781299241381 |
1299241387 |
9781118397206 |
1118397207 |
9781118397169 |
1118397169 |
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Descrizione fisica |
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1 online resource (215 p.) |
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Collana |
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ULLA postgraduate pharmacy series |
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Altri autori (Persone) |
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TrainiDaniela |
ButtiniFrancesca |
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Disciplina |
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Soggetti |
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Respiratory therapy |
Drug delivery systems - Methodology |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Inhalation Drug Delivery: Techniques and Products; Contents; List of contributors; Series foreword; Preface; 1 Inhalation drug delivery; 1.1 Introduction; 1.2 Brief review of the respiratory system and its physiology; 1.3 Deposition and the fate of particles in the respiratory tract; 1.4 Deposition mechanisms; 1.5 Parameters influencing particle deposition; 1.6 The clearance of deposited particles; 1.7 Airways geometry and humidity; 1.8 Lung clearance mechanisms; 1.9 Local and systemic drug delivery; 1.10 Conclusion; References; 2 Inhalation and nasal products; 2.1 Introduction |
2.2 Dry powder inhalers (DPIs)2.3 Liquid and propellant-based inhalers; 2.3.1 Pressurized metered-dose inhalers (pMDIs); 2.3.2 Nebulizers; 2.4 Nasal formulations; 2.4.1 Nasal physiology; 2.4.2 Delivery issues and concerns; 2.4.3 Strategy for enhanced nasal delivery; 2.4.4 Marketed nasal products; 2.4.5 Pharmaceutical development studies for nasal |
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products; 2.5 Conclusion; References; 3 Formulation of inhalation medicines; 3.1 Introduction; 3.2 Pressurized metered-dose inhaler (pMDI) formulation; 3.2.1 Suspension technology; 3.2.2 Solution technology; 3.3 Dry powder inhaler (DPI) formulation |
3.3.1 Carrier technology3.3.2 Agglomerate technology; 3.4 Conclusion; References; 4 Novel particle production technologies for inhalation products; 4.1 Introduction; 4.2 Conventional crystallization and milling; 4.3 Specialized milling; 4.3.1 Fluid-energy milling at elevated humidity; 4.3.2 Wet-milling nanotechnology; 4.4 Solvent precipitation; 4.4.1 Sono-crystallization; 4.4.2 Microprecipitation by opposing liquid jets and tangential liquid jets; 4.4.3 High-gravity controlled precipitation; 4.5 Spray-drying and related droplet evaporation methods; 4.5.1 Spray-drying |
4.5.2 Controlled evaporation of droplets4.5.3 Evaporation of low-boiling-point solutions; 4.5.4 Spray freeze-drying; 4.6 Supercritical fluid (SCF) technology; 4.7 Conclusion; Acknowledgements; References; 5 Methods for understanding, controlling, predicting, and improving drug product performance; 5.1 Introduction; 5.1.1 The complexities and challenges of aerosol performance; 5.1.2 Understanding powder/particle characteristics: implications for aerosol product performance; 5.1.3 Liquid systems; 5.1.4 Summary; 5.2 Particle sizing; 5.2.1 Sieve analysis; 5.2.2 Image analysis; 5.2.3 Light scatter |
5.2.4 Time-of-flight5.2.5 Other methods; 5.3 Powder and particulate characterization systems; 5.3.1 Introduction; 5.3.2 Powder cohesion and adhesion; 5.3.3 Microscopic material characterization; 5.3.4 Methods for studying bulk powders; 5.4 Practical issues in process control; 5.4.1 Common primary and secondary processing methods and issues arising for control; 5.5 Biopharmaceutical powder stability; 5.6 Liquids: solutions and suspensions; 5.6.1 Liquid formulation stability; 5.7 Conclusion; References |
6 Aerodynamic assessment for inhalation products: fundamentals and current pharmacopoeial methods |
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Sommario/riassunto |
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"Provides students and those in industry with concise clear guide to the essential fundamentals in inhalation drug delivery"--Provided by publisher. |
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