Synthesis and metabolism of adrenocortical steroids / / consulting editor for volume, W. Klyne ; editors for the Ciba Foundation, G. E. W. Wolstenholme, Margaret P. Cameron

• Record Nr.: UNINA9911019872303321
• Pubbl/distr/stampa: Boston, : Little, Brown, 1953
• ISBN: 9786613679178; 9781280768408; 1280768401; 9780470718865; 0470718862; 9780470716267; 0470716266
• Descrizione fisica: 1 online resource (320 p.)
• Collana: Ciba Foundation Colloquia on endocrinology ; ; v. 7
• Altri autori (Persone): KlyneWilliam; CameronMargaret P; WolstenholmeG. E. W (Gordon Ethelbert Ward)
• Disciplina: 612; 612.45
• Soggetti: Adrenocortical hormones; Endocrinology
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: CIBA FOUNDATION COLLOQUIA ON ENDOCRINOLOGY; Foreword by the Chairman; Steroid Nomenclature; Steroids from the adrenal gland and related steroids (Table); CONTENTS; Companion substances in cholesterol of various sources; Discussion; The chemistry of lanosterol; Discussion; The ergosterol route to adrenal cortical hormones; Discussion; Investigations on the synthesis of 11- ketosteroids; Discussion; Partial synthesis of D9(11)-anhydrocorticosterone acetate; Discussion; Cortisone and 11-epi-17- hydroxycorticosterone diacetate from sarmentogenin; Discussion; Synthesis of 11-oxygenated steroids from steroidal sapo- geninsDiscussion; 11-Oxygenated steroids from ergosteryl-D acetate ; 22:23- dibromide; Discussion; Introduction of the 11-keto function in the steroids; Discussion; The characterization of trisubstituted steroidal olefines by infra-red spectroscopy; Discussion; Some aspects of the stereochemistry of C-20; Discussion; The chemical action of X-rays on some steroids in aqueous systems; Discussion; Biogenesis of adrenal cortical hormones; Discussion; Studies of the enzymes involved in the synthesis and degra- dation of the hormones of the adrenal cortexThe in nitro synthesis of adrenal cortical steroids; Discussion; Species differences and other factors influencing adreno- cortical secretion; Discussion; In vivo metabolism of adrenosterone; Current status of corticosteroid metabolism in man; Discussion; Estimation of individual adrenocortical hormones in human peripheral blood; Discussion; Corticosteroid metabolism in isolated perfused rat livers; Discussion
• Sommario/riassunto: The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.