1.

Record Nr.

UNINA9910786096103321

Autore

Cross Barry L.

Titolo

Lean innovation : understanding what's next in today's economy / / Barry L. Cross

Pubbl/distr/stampa

Boca Raton : , : CRC Press, , 2013

ISBN

1-4665-8891-8

0-429-25364-8

1-4665-8890-X

1-4665-1526-0

Edizione

[1st edition]

Descrizione fisica

1 online resource (209 p.)

Disciplina

658.4/063

658.4063

Soggetti

Technological innovations

Creative ability in technology

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Front Cover; Contents; Acknowledgments; Introduction; Chapter 1 - The Need for Innovation; Chapter 2 - What's Lean Got to Do with It?; Chapter 3 - The Innovation Framework; Chapter 4 - Innovation Culture; Chapter 5 - Generating Ideas; Chapter 6 - Refining Ideas; Chapter 7 - Spreading the Ideas for Adoption; Chapter 8 - Back to Culture; Appendix 1: Fearless Predictions and Things to Create or Kill; Appendix 2: More Thoughts on Lean; About the Author; Back Cover

Sommario/riassunto

Do these comments sound familiar? We would love to be more innovative, but we don't have the resources Innovation works in some companies; we just aren't that creative We get some good ideas, but nothing ever happens with them Unfortunately, they reflect the general perception and environment for innovation in many firms today. In Lean Innovation: Understanding What's Next in Today's Economy, Barry Cross explores how to use Lean to free up resources from within the organization to support and 'fund' innovation and inspire a culture of creativity. Easy to read and humorous, Cross' stories reson



2.

Record Nr.

UNISALENTO991004324436207536

Autore

Bruno, Giordano, <1548-1600>

Titolo

De la causa, principio e uno / Giordano Bruno ; introduzione e commento di Augusto Guzzo

Pubbl/distr/stampa

Firenze : Sansoni, stampa 1955

Titolo uniforme

De la causa, principio et uno 156076

Descrizione fisica

XLIII, 167 p. ; 20 cm

Collana

Collana scolastica di testi filosofici

Altri autori (Persone)

Guzzo, Augusto

Disciplina

195

Soggetti

Causalità - Concezione [di] Bruno, Giordano

Lingua di pubblicazione

Italiano

Formato

Materiale a stampa

Livello bibliografico

Monografia



3.

Record Nr.

UNINA9911019815803321

Titolo

Acetaldehyde-related pathology : bridging the trans-disciplinary divide / / [chair, Peter Emery]

Pubbl/distr/stampa

Chichester ; ; Hoboken, N.J., : John Wiley, 2007

ISBN

9786610855988

9781280855986

1280855983

9780470511848

0470511842

9780470511831

0470511834

Edizione

[8th ed.]

Descrizione fisica

1 online resource (287 p.)

Collana

Novartis Foundation symposium ; ; 285

Altri autori (Persone)

EmeryPeter <1953->

ChadwickDerek

GoodeJamie

Disciplina

615.952

Soggetti

Acetaldehyde - Toxicology

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Editors: Derek J. Chadwick and Jamie Goode.

Nota di bibliografia

Includes bibliographical references and indexes.

Nota di contenuto

Acetaldehyde-Related Pathology: Bridging the Trans-Disciplinary Divide; Contents; Chair's introduction; Acetaldehyde generating enzyme systems: roles of alcohol dehydrogenase, CYP2E1 and catalase, and speculations on the role of other enzymes and processes; Removal of acetaldehyde from the body; Acetaldehyde, polymorphisms and the cardiovascular system; Acetaldehyde and alcoholic cardiomyopathy: lessons from the ADH and ALDH2 transgenic models; Interrelationship between alcohol, smoking, acetaldehyde and cancer; Effects of acetaldehyde on human airway constriction and inflammation

The role of acetaldehyde in alcohol-associated cancer of the gastrointestinal tractThe determination of acetaldehyde in exhaled breath; Ethanol and acetaldehyde: in vivo quantitation and effects on cholinergic function in rat brain; Pharmacological treatments and strategies for reducing oral and intestinal acetaldehyde; Alcoholic myopathy and acetaldehyde; Acetaldehyde adducts in circulation;



General discussion; Pancreatic MAP kinase pathways and acetaldehyde; Acetaldehyde alters MAP kinase signalling and epigenetic histone modifications in hepatocytes

Endogenous a-oxoaldehydes and formation of protein and nucleotide advanced glycation endproducts in tissue damageMeasurement of acetaldehyde: what levels occur naturally and in response to alcohol?; Final discussion; Contributors Index; Subject index

Sommario/riassunto

Part of the prestigious Novartis Foundation, this is the first book to review the pathology associated with acetaldehyde, a known toxic agent found in cigarette smoke and other pollutants and derived from ingested alcohol, amongst other sources. In the body, acetaldehyde affects several tissues, particularly the brain and liver, causing various diseases, including cancer, alcoholic liver disease and Alzheimer's. Acetaldehyde-Related Pathology describes the toxic effects of acetaldehyde at the tissue and cellular levels, reviewing enzyme biochemistry, transgenic mouse models of