1.

Record Nr.

UNINA9911019795603321

Titolo

Vector targeting for therapeutic gene delivery

Pubbl/distr/stampa

[Place of publication not identified], : Wiley Liss, 2002

ISBN

1-280-55647-1

9786610556472

0-471-46116-4

0-471-23430-3

Descrizione fisica

1 online resource (716 pages)

Disciplina

616.042

Soggetti

Genetic Therapy - methods

Genetic Vectors

Gene Expression Regulation, Viral - genetics

Transduction, Genetic - methods

Pathology

Medicine

Health & Biological Sciences

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Bibliographic Level Mode of Issuance: Monograph

Sommario/riassunto

"...very informative and comprehensive...belongs on the shelf of every library and lab providing essential resources for research on vector design or delivery." - Cancer Biology and Therapy. This comprehensive volume presents the most recent advances in target definition technology and provides a detailed overview on the rational design of targeted vectors for gene therapy. A theoretical framework for advanced vector design is provided that integrates all of the allied sciences relevant to the study of vector targeting. The text discusses the basic underlying science and then leads to discussions of the various viral vectors and methods of defining targets. Finally, an expert outlook on promising therapeutic applications is offered.