1.

Record Nr.

UNINA9911019694503321

Titolo

Steroids and neuronal activity

Pubbl/distr/stampa

Chichester, West Sussex, England ; ; New York, : Wiley, 1990

ISBN

9786612347672

9781282347670

1282347675

9780470513989

0470513985

9780470513996

0470513993

Descrizione fisica

1 online resource (296 p.)

Collana

Ciba Foundation symposium ; ; 153

Altri autori (Persone)

ChadwickDerek

WiddowsKate

Disciplina

612.8/14

Soggetti

Neuroendocrinology

Steroid hormones - Physiological effect

Neurons

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

"Symposium on Steroids and Neuronal Activity, held at the Ciba Foundation, London, 23-25 January 1990"--P. v.

"A Wiley-Interscience publication."

Editors: Derek Chadwick, organizer, and Kate Widdows.

Nota di bibliografia

Includes bibliographical references and indexes.

Nota di contenuto

STEROIDS AND NEURONAL ACTIVITY; Contents; Introduction; Steroid effects on neuronal activity: when is the genome involved?; Neuroendocrine metabolism of progesterone and related progestins; Steroid modulation of the GABAA receptor complex: electrophysiological studies; Steroid regulation of the GABAA receptor: ligand binding, chloride transport and behaviour; Steroid binding at si receptors: CNS and immunological implications; General discussion I : Gene-mediated corticosteroid effects on neuronal excitability; Effects of progesterone and its metabolites on neuronal membranes

In vitro effects of 17B-oestradiol on the sensitivity of receptors coupled to adenylate cyclase on striatal neurons in primary cultureEffect of



oestradiol on dopamine receptors and protein kinase C activity in the rat pituitary: binding of oestradiol to pituitary membranes; The molecular features of membrane perturbation by anaesthetic steroids: a study using differential scanning calorimetry, small angle X-ray diffraction and solid state 2H NMR; Effects of prostaglandin E2 and progesterone on rat brain synaptosomal plasma membranes; Steroids and neuronal destruction or stabilization

General discussion II : Sex differences in GABA-mediated responsesSteroids in relation to epilepsy and anaesthesia; Early and late effects of steroid hormones on the central nervous system; Final general discussion : Use of adrenal corticosteroids in sports; Steroids and anaesthesia; Role of steroids in the brain; Genomic or non-genomic?; Summing-up; Index of contributors; Subject index

Sommario/riassunto

Classical studies of steroid hormones are concerned with their regulation of protein synthesis via the modulation of genomic transcription. But many of the actions of these hormones occur too rapidly to be explained in this manner, particularly their effects on the central nervous system. This text deals with recent discoveries showing that steroids can modulate the activity of some neurotransmitters. It explores the role of GABA as an important regulator of neuronal activity in the central nervous system and its inhibitory action as mediated via the GABA receptor and potentiated by steroids.



2.

Record Nr.

UNINA9910711192603321

Autore

Seabaugh Alan Carter

Titolo

EPROP : an interactive FORTRAN program for computing selected electronic properties of gallium arsenide and silicon / / Alan C. Seabaugh, John J. Mathias, Michael I. Bell

Pubbl/distr/stampa

Gaithersburg, MD : , : U.S. Dept. of Commerce, National Institute of Standards and Technology, , 1990

Descrizione fisica

1 online resource

Collana

NIST special publication ; ; 400-85

Altri autori (Persone)

BellMichael I

MathiasJohn J

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

1990.

Contributed record: Metadata reviewed, not verified. Some fields updated by batch processes.

Title from PDF title page.

Nota di bibliografia

Includes bibliographical references.