1.

Record Nr.

UNINA9911019645603321

Titolo

Ciba Foundation Symposium : complement / / edited by G.E.W. Wolstenholme and Julie Knight

Pubbl/distr/stampa

London, : J. & A. Churchill, 1965

ISBN

9786613679376

9781280768606

1280768606

9780470719381

0470719389

9780470716922

0470716924

Edizione

[1st ed.]

Descrizione fisica

1 online resource (418 p.)

Collana

Ciba Foundation symposium

Altri autori (Persone)

WolstenholmeG. E. W (Gordon Ethelbert Ward)

KnightJulie

Disciplina

616.07/9

Soggetti

Complement (Immunology)

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and indexes.

Nota di contenuto

COMPLEMENT; Preface; Editors' note; Contents; Chairman's introduction; Mechanism of haemolysis by complement; Discussion; Nomenclature and fixation of C'3 components; Identity of complement components from different species; Enzymic nature of C'2; Binding of C'2 to EAC'1,4 cells; Definition of complement; Small molecular weight inhibitors of complement action; Discussion; Mechanisms of activation of C'1 and inhibition of C'1 esterase; Discussion; Problems in determining the sites of synthesis of complement components; Discussion; Mechanism of the damage-producing steps of immune haemolysis

DiscussionEffects of complement on sensitized nucleated cells; Discussion; Immune bactericidal and bacteriolytic reactions; Discussion; Electron microscope studies of immune cell lysis; Discussion; Complement and the activity of phagocytes; Discussion; lmmune adherence; Discussion; Complement, conglutinin and immuno-conglutinins; Discussion; Differentiation in vitro of antigen-



induced histamine release from complement-dependent immune injury; Discussion; The possible rôle of complement in autoaggressive processes; Discussion; The rôle of complement in haemolytic processes in vivo; Discussion

Complement and the paroxysmal nocturnal haemoglobinuria red cellDiscussion; General Discussion; Standard preparations of complement components; Characteristics of human red cells; Complement in disease processes; Effects of complement deficiency; Rôle of complement in delayed hypersensitivity reactions; Chairrnan's closing remarks; Author index; Subject index

Sommario/riassunto

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.