U.S. Navy codebreakers, linguists, and intelligence officers against Japan, 1910-1941 : a biographical dictionary / / Capt. Steven E. Maffeo

• Record Nr.: UNINA9910797852003321
• Autore: Maffeo Steven E.
• Pubbl/distr/stampa: Lanham, MD : , : Rowan & Littlefield, , [2016]; ©2016
• ISBN: 1-4422-5564-1
• Descrizione fisica: 1 online resource (575 p.)
• Disciplina: 359.3/432092273
• Soggetti: Cryptographers - United States; Linguists - United States; Intelligence officers - United States; World War, 1939-1945 - Cryptography; World War, 1939-1945 - Campaigns - Japan
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Contents; Acronyms and Abbreviations; Foreword; Author's Foreword; Acknowledgments; Introduction; Illustrations; The Scanners. Radio Direction Finders and Radio Traffic Analysts; The Book Breakers. Cryptographers, Cryptanalysts, and Codebreakers; The Blue Sky Merchants. Linguists, Translators, and Intelligence Officers; The "Hybrids". Multiskilled and Multiproficient; Appendix A. What's a Code, and What's a Cipher?; Appendix B. Chronology of Select Highlights, U.S. Navy Radio Intelligence, Pacific Area of Operations 1916-1941; Appendix C. Directors of U.S. Naval Intelligence, 1909-1942; Appendix D. Directors of U.S. Naval Communications 1912-1942Appendix E. U.S. Naval Attachés in Tokyo, 1914-1941; Appendix F. U.S. Navy, Office of the Chief of Naval Operations, Section "OP-20-G" and Its Antecedents; Appendix G. Officers in Charge, Office of Naval Communications, Code and Signal Section, "Research Desk" (OP-20-GX); Appendix H. Officers in Charge, Office of Naval Communications, Code and Signal Section, Translation Section (OP-20-GZ); Appendix I. Growth of U.S. Navy Radio Intelligence; Appendix J. U.S. Naval Radio Intelligence, Primarily Focused upon Japan, as of December 1941; Appendix K. Station HYPO, Territory of HawaiiAppendix L. U.S. Navy and U.S. Marine Corps Japanese Language/Culture Officers Immersed in Japan, 1910-1941; Appendix M. The "On-the-Roof Gang"; Appendix N. Operation VENGEANCE; Suggested Reading; Glossary; Index; About the Author
• Sommario/riassunto: This unique reference presents 59 biographies of people who were key to the sea services being reasonably prepared to fight the Japanese Empire when the Second World War broke out, and whose advanced work proved crucial. These intelligence pioneers invented techniques, procedures, and equipment from scratch, not only allowing the United States to hold its own in the Pacific despite the loss of most of its Fleet at Pearl Harbor, but also laying the foundation of today's intelligence methods and agencies.

Proteomic and genomic analysis of cardiovascular disease / / edited by Jennifer E. Van Eyk and Michael J. Dunn

• Record Nr.: UNINA9911019629503321
• Pubbl/distr/stampa: Weinheim, : [Cambridge], : Wiley-VCH, c2003
• ISBN: 9786610520541; 9781280520549; 128052054X; 9783527605453; 3527605452; 9783527601523; 352760152X
• Descrizione fisica: 1 online resource (426 p.)
• Altri autori (Persone): Van EykJennifer E. <1959->; DunnMichael J. <1936->
• Disciplina: 572.6; 616.1/042; 616.1042
• Soggetti: Cardiovascular system - Diseases - Genetic aspects; Proteomics
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Proteomic and Genomic Analysis of Cardiovascular Disease; Preface; Contents; List of Contributors; Abbreviations; Section 1 Genomics; 1 Large Scale Expression Profiling in Cardiovascular Disease Using Microarrays: Prospects and Pitfalls; 1.1 DNA Microarray Technologies; 1.1.1 cDNA Microarrays or Oligonucleotide Arrays?; 1.1.2 Designing Meaningful Experiments; 1.2 Computational Analysis of Microarray Data; 1.2.1 Raw Data Analysis; 1.2.2 Comparing Expression Data; 1.2.3 Clustering Algorithms; 1.2.4 Data Sharing; 1.3 Potential Use of this Technology in Understanding Complex Heart Disease; 1.4 Acknowledgements1.5 References; 2 Global Genomic Analyses of Cardiovascular Disease: A Potential Map or Blind Alley?; 2.1 Blindly Searching for Structure-Function; 2.2 The Starting Line: Garbage In - Garbage Out?; 2.3 Is the Mouse a Valid Model for Human-Based Disease Transcriptome Studies?; 2.4 Arrays and Cardiovascular Disease; 2.5 Filtering the Transcriptome: Enhancing the Value; 2.6 Concluding Remarks; 2.7 References; 3 Heart Failure: A Genomics Approach; 3.1 Overview of Heart Failure; 3.2 Pathophysiology of Heart Failure; 3.3 Genomic Approach to Heart Failure; 3.4 Conclusion; 3.5 Acknowledgements3.6 References; 4 Principles of cDNA Microarrays as Applied in Heart Failure Research; 4.1 The Clinical Problem; 4.2 The Need for a New Paradigm; 4.3 The Potential Role of the Microarray; 4.4 Strengths of Microarray Technology; 4.5 Caveats of Using the Microarray Technology; 4.6 Experimental Design; 4.7 Tissue Preparation and Preservation; 4.8 RNA Isolation; 4.9 RNA Amplification; 4.10 Probe Labeling; 4.11 Data Analysis and Bioinformatics; 4.12 Application: New Classification of Disease; 4.13 Application: Pathogenesis of Disease; 4.14 Application: Early Disease Markers and Prognosis4.15 Application: Therapeutic Insights; 4.16 Acknowledgements; 4.17 References; 5 Gene Profiling in the Heart by Subtractive Hybridization; 5.1 Strategies and Limitations of Genome Profiling; 5.1.1 The Biological Problem; 5.1.2 The Model; 5.1.3 The Technological Approach; 5.2 Analyzing Gene Expression by Subtractive Hybridization; 5.2.1 Methodology; 5.2.2 Advantages and Disadvantages; 5.3 Genomics of Myocardial Ischemia; 5.4 Subtractive Hybridization of Myocardial Ischemia; 5.4.1 Myocardial Stunning; 5.4.2 Genomic Profile of Myocardial Stunning5.4.3 Chasing Novel Genes; 5.5 Summary; 5.6 Acknowledgements; 5.7 References; 6 DNA Microarray Gene Profiling: A Tool for the Elucidation of Cardioprotective Genes; 6.1 Introduction; 6.2 Candidates for Cardioprotective Genes and Possible Mechanism(s) of Protection; 6.2.1 Candidate Genes Involved in Cardioprotection; 6.2.2 Potential Mechanisms of Cardioprotection; 6.3 Is There a Common Set of Cardioprotective Genes?; 6.4 Effects of Long-term Activation and Dosage of Cardioprotective Genes; 6.5 Approaches to Identify Genes Involved in Cardioprotection; 6.5.1 Preconditioning
• Sommario/riassunto: This is the very first book to focus on this new approach that will eventually aid in developing new diagnostic markers and therapies for controlling and treating heart disease - the number-one killer in the industrialized world.Divided into two parts, the book describes not only the potentials, but also the limitations of these technologies. The editors, both well known within the scientific community, provide new insights into the biochemical and cellular mechanisms of cardiovascular disease, as well as covering the transition into clinical applications. In so doing, they highlight the v