1.

Record Nr.

UNINA9911019576803321

Titolo

Mutation as cellular process : a Ciba Foundation symposium / / edited by G.E.W. Wolstenholme and Maeve O'Connor

Pubbl/distr/stampa

London, : J. & A. Churchill Ltd., 1969

ISBN

9786613618313

9781280588488

1280588489

9780470719718

0470719710

9780470717349

0470717343

Descrizione fisica

1 online resource (258 p.)

Collana

Novartis Foundation Symposia ; ; v.996

Altri autori (Persone)

WolstenholmeG. E. W (Gordon Ethelbert Ward)

O'ConnorMaeve

Disciplina

575.2/92

Soggetti

Mutagenesis

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

"With 48 illustrations"--T.p. verso.

Nota di bibliografia

Includes bibliographical references and indexes.

Nota di contenuto

MUTATION AS CELLULAR PROCESS; Contents; Chairman's opening remarks; Influence of the host on the induction and expression of mutations in phage kappa; Discussion; Influence of cellular physiology on the realization of mutations-results and prospects; Discussion; Enhancement and diminution of ultraviolet-light- initiated mutagenesis by post-treatment with caffeine in Escherichia coli; Allele-specific responses t o factors that modify U.V. mutagenesis; Discussion; Analysis of a case of mutagen specificity in Neurospora crassa; Discussion

Repair of latent T5-resistant mutants in chemostat culturesDiscussion; General Discussion; The nature and influence of ultraviolet and hydroxylamine lesions in nucleic acids and the enzymic repair of the former; Discussion; Nature of alkylation lesions and their repair: significance for ideas on mutagenesis; Discussion; The effect of ribosome alterations on ribosome function, and on expression of ribosome and non- ribosome mutations; Discussion; Aspects of



modification of nucleic acids in mutational processes; Discussion; Relationships between recombination and mutation; Discussion

General DiscussionObserved mutation frequency in mice and the chain of processes affecting it; Discussion; Final Discussion; Author index; Subject index

Sommario/riassunto

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.