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1. |
Record Nr. |
UNISOBE600200018731 |
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Autore |
Frabboni, Franco |
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Titolo |
La scuola elementare / Franco Frabboni |
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Pubbl/distr/stampa |
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Firenze, : La Nuova Italia, 1977 |
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Descrizione fisica |
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Collana |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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2. |
Record Nr. |
UNISA996391547703316 |
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Autore |
Maunsell Andrew <d. 1595.> |
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Titolo |
The first part of the catalogue of English printed bookes [[electronic resource] ] : vvhich concerneth such matters of diuinitie, as haue bin either written in our owne tongue, or translated out of anie other language: and haue bin published, to the glory of God, and edification of the Church of Christ in England. Gathered into alphabet, and such method as it is, by Andrew Maunsell, bookeseller |
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Pubbl/distr/stampa |
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London, : Printed by Iohn VVindet [and James Roberts] for Andrew Maunsell, dwelling in Lothburie, 1595 |
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Descrizione fisica |
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[8], 123, [1]; [6], 27, [1] p |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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"The seconde parte of the catalogue .. which concerneth the sciences" has separate pagination and register, and title page with imprint "At London, printed by Iames Roberts, for Andrew Maunsell, dwelling in Lothburie. 1595.". |
Reproduction of the original in the Henry E. Huntington Library and Art Gallery. |
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3. |
Record Nr. |
UNINA9911019439603321 |
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Titolo |
Carbohydrate-based drug discovery / / Chi-Huey Wong (ed.) |
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Pubbl/distr/stampa |
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Weinheim ; ; [New York], : Wiley-VCH, c2003 |
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ISBN |
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9786610520725 |
9781280520723 |
1280520728 |
9783527605781 |
3527605789 |
9783527602438 |
3527602437 |
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Descrizione fisica |
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1 online resource (981 p.) |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Carbohydrate drugs |
Carbohydrates - Synthesis |
Glycoconjugates - Physiological effect |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Carbohydrate-based Drug Discovery; Contents; Preface; List of Contributors; Volume 1; 1 Synthetic Methodologies; 1.1 Introduction; 1.2 Tactical Analysis for Overall Synthetic Efficiency; 1.3 Methodological Improvements; 1.3.1 Chemistry; 1.3.2 Protecting Group Manipulations; 1.3.3 Modulation of the Reactivity of Glycosyl Donors; 1.3.4 Block Synthesis; 1.4 Accessibility; 1.4.1 Solution-based Chemistry; 1.4.2 One-Pot Glycosylation; 1.4.3 Solid-Phase Chemistry; 1.4.3.1 Fundamentals of Solid-Phase Oligosaccharide Synthesis; 1.4.3.2 The Support; 1.4.3.3 Linkers to the Support |
1.4.3.4 Protecting Groups used in Solid-Phase Oligosaccharide Synthesis1.4.3.5 Solid-Phase Oligosaccharide Synthesis; 1.4.3.6 Monitoring of Reaction Progress; 1.4.4 Automation; 1.5 Concluding |
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Remarks; 1.6 References; 2 Complex Carbohydrate Synthesis; 2.1 Introduction; 2.2 Synthetic Gangliosides; 2.2.1 Gangliosides GM4 and GM3, and their Analogues and Derivatives; 2.2.2 Sialylparagloboside (SPG) Analogues and Derivatives; 2.2.3 Selectin Ligands; 2.2.3.1 Sialyl Lewis x; 2.2.3.2 Novel 6-Sulfo sLe(x) Variants; 2.2.4 Siglec Ligands; 2.2.4.1 Chol-1 (α-Series) Gangliosides |
2.2.4.2 Novel Sulfated Gangliosides2.3 Toxin Receptor; 2.4 Summary and Perspectives; 2.5 References; 3 The Chemistry of Sialic Acid; 3.1 Introduction; 3.2 Chemical and Enzymatic Synthesis of Sialic Acids; 3.3 Chemical Glycosidation of Sialic Acids; 3.3.1 Direct Chemical Sialylations; 3.3.1.1 2-Chloro Derivatives as Glycosyl Donors; 3.3.1.2 2-Thio Derivatives as Glycosyl Donors; 3.3.1.3 2-Xanthates as Glycosyl Donors; 3.3.1.3 2-Phosphites as Glycosyl Donors; 3.3.1.4 Miscellaneous Direct Chemical Methods; 3.3.2 Indirect Chemical Methods with the Use of a Participating Auxiliary at C-3 |
4.3.2 Immobilization of the Glycosyl Donor4.3.3 Bi-directional Strategy; 4.4 Support Materials; 4.4.1 Insoluble Supports; 4.4.2 Soluble Supports; 4.5 Linkers; 4.5.1 Silyl Ethers; 4.5.2 Acid- and Base-Labile Linkers; 4.5.3 Thioglycoside Linkers; 4.5.4 Linkers Cleaved by Oxidation; 4.5.5 Photocleavable Linkers; 4.5.6 Linkers Cleaved by Olefin Metathesis; 4.6 Synthesis of Oligosaccharides on Solid Support by Use of Different Glycosylating Agents; 4.6.1 1,2-Anhydrosugars - The Glycal Assembly Approach; 4.6.2 Glycosyl Sulfoxides; 4.6.3 Glycosyl Trichloroacetimidates; 4.6.4 Thioglycosides |
4.6.5 Glycosyl Fluorides |
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Sommario/riassunto |
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To exploit the full potential of this diverse compound class for the development of novel active substances, this handbook presents the latest knowledge on carbohydrate chemistry and biochemistry. While it is unique in covering the entire field, particular emphasis is placed on carbohydrates with pharmaceutical potential.Topics include the following:> Chemical Synthesis of Carbohydrates> Carbohydrate Biosynthesis and Metabolism> Carbohydrate Analysis> Cellular Functions of Carbohydrates> Development of Carbohydrate-based DrugsA premier resource for carbohydrate chem |
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