1.

Record Nr.

UNINA9911019218403321

Autore

Vorbruggen Helmut

Titolo

Silicon-mediated transformations of functional groups / / Helmut Vorbruggen

Pubbl/distr/stampa

Weinheim, : Wiley-VCH, c2004

ISBN

9786610520800

9781280520808

1280520809

9783527603770

3527603778

9783527605927

3527605924

Descrizione fisica

1 online resource (378 p.)

Disciplina

547.2

Soggetti

Functional groups

Silicon

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and indexes.

Nota di contenuto

Silicon-mediated Transformations of Functional Groups; Contents; Preface; 1 Introduction; 2 Techniques for Preparative Silylations-Desilylations; 3 Preparation and Properties of Silyloxy Leaving Groups; 4 Reactions of Free and Derivatized Carboxylic Acids and Carbon Dioxide; 5 Reactions of Aldehydes and Ketones; 6 Reactions of Alcohols, Esters, Silyl Ethers, Epoxides, and Haloalkanes; 7 Reactions of N-O Systems; 8 Reactions of S-O and Se-O Systems; 9 Cyclizations and Ring Enlargements; 10 Base-catalyzed, Acid-catalyzed and Thermal Eliminations of Trimethylsilanol. Peterson Reactions

11 Formation of Carbon-Phosphorus Double Bonds12 Reductions and Oxidations; 13 Dehydration-Halogenation-Activation and Silylation of Inorganic and Organic Salts and Metallorganic Compounds; 14 Formation of Organic and Inorganic Polymers; Appendix; Subject Index; Author Index

Sommario/riassunto

In the first work to comprehensively cover this all-important topic, the recognized expert Helmut Vorbr?ggen provides both organic and



bioorganic chemists with much new and valuable information for preparative synthesis. Although every organic chemist may be familiar with different aspects of silylation for the protection of functional groups, this book covers the concept of protection while simultaneously silylating-activating various functional groups, such as amides and ureas. This novel methodology opens thus numerous synthetic pathwayswhile effecting the elimination of water in it