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1. |
Record Nr. |
UNISA996393335903316 |
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Autore |
Canisius Petrus, Saint, <1521-1597.> |
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Titolo |
Certayne necessarie principles of religion, which may be entituled, A catechisme conteyning all the partes of the Christian and Catholique fayth [[electronic resource] /] / written in Latin by P. Canitius . |
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Pubbl/distr/stampa |
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Duaci [i.e. London?], : Per Ioannem Bogardum [i.e. William Carter?], [1579?] |
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Descrizione fisica |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Translation of and additions to Parvus catechismus Catholicorum--Cf. NUC pre-1956 imprints. |
Running title: A catechisme for Catholiques. |
Corrections to possible fictitious imprint suggested by STC (2nd ed.) and NUC pre-1956 imprints. |
Signatures: [par.]â¸(-par.1) A-Hâ¸. |
Imperfect: signature [par.]8 lacking; stained and tightly bound with slight loss of print. |
Reproduction of original in the British Library. |
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Sommario/riassunto |
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2. |
Record Nr. |
UNINA9910298433003321 |
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Titolo |
RNA Metabolism in Neurodegenerative Diseases / / edited by Rita Sattler, Christopher J. Donnelly |
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Pubbl/distr/stampa |
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
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ISBN |
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Edizione |
[1st ed. 2018.] |
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Descrizione fisica |
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1 online resource (321 pages) |
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Collana |
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Advances in Neurobiology, , 2190-5215 ; ; 20 |
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Disciplina |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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RNA Metabolism in Neurodegenerative Diseases -- Mechanism of Splicing Regulation of Spinal Muscular Atrophy Genes -- RNA Editing Deficiency in Neurodegeneration -- RNA Nucleocytoplasmic Transport Defects in Neurodegenerative Diseases -- RNA Degradation in Neurodegenerative Disease -- RNP Assembly Defects in Spinal Muscular Atrophy -- Stress Granules and ALS: A Case of Causation or Correlation? -- Deregulation of RNA Metabolism in Microsatellite Expansion Diseases -- Mechanisms Associated with TDP-43 Neurotoxicity in ALS/FTLD -- Senataxin, a Novel Helicase at the Interface of RNA Transcriptome Regulation and Neurobiology: From Normal Function to Pathological Roles in Motor Neuron Disease and Cerebellar Degeneration -- Lost in Translation – Evidence for Protein Synthesis Deficits in ALS/FTD and Related Neurodegenerative Diseases. |
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Sommario/riassunto |
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It has become evident over the last years that abnormalities in RNA processing play a fundamental part in the pathogenesis of neurodegenerative diseases. Cellular viability depends on proper regulation of RNA metabolism and subsequent protein synthesis, which requires the interplay of many processes including transcription, pre‐mRNA splicing, mRNA editing as well as mRNA stability, transport and translation. Dysfunction in any of these processes, often caused by mutations in the coding and non‐coding RNAs, can be very destructive to the cellular environment and consequently impair neural viability. The result of this RNA toxicity can lead to a toxic gain of function or a |
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loss of function, depending on the nature of the mutation. For example, in repeat expansion disorders, such as the newly discovered hexanucleotide repeat expansion in theC9orf72 gene found in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), a toxic gain of function leads to the formation of RNA foci and the sequestration of RNA binding proteins (RBPs). This in return leads to a loss of function of those RBPs, which is hypothesized to play a significant part in the disease progression of ALS and FTD. Other toxicities arising from repeat expansions are the formation of RNA foci, bi‐directional transcription and production of repeat associated non‐ATG (RAN) translation products. This book will touch upon most of these disease mechanisms triggered by aberrant RNA metabolism and will therefore provide a broad perspective of the role of RNA processing and its dysfunction in a variety of neurodegenerative disorders, including ALS, FTD, Alzheimer’s disease, Huntington’s disease, spinal muscular atrophy, myotonic dystrophy and ataxias. The proposed authors are leading scientists in the field and are expected to not only discuss their own work, but to be inclusive of historic as well as late breaking discoveries. The compiled chapters will therefore provide a unique collection of novel studies and hypotheses aimed to describe the consequences of altered RNA processing events and its newest molecular players and pathways. |
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3. |
Record Nr. |
UNINA9911019094303321 |
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Titolo |
Proceedings of the 21st annual Conference on Composites, Advanced Ceramics, Materials, and Structures : January 12-16, 1997, Cocoa Beach, FL / / J.P. Singh, program chair |
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Pubbl/distr/stampa |
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Westerville, OH, : American Ceramic Society, c1997 |
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ISBN |
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9786612313615 |
9781282313613 |
1282313614 |
9780470294437 |
0470294434 |
9780470294925 |
0470294922 |
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Descrizione fisica |
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1 online resource (812 p.) |
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Collana |
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Ceramic engineering & science proceedings, , 0196-6219 ; ; v. 18/3 |
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Altri autori (Persone) |
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SinghJitendra Prasad <1946-> |
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Disciplina |
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Soggetti |
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Composite materials |
Ceramic materials |
Structural analysis (Engineering) |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and indexes. |
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Nota di contenuto |
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Ceramic Engineering & science Proceedings Volume 18, Issue 3, 1997; Foreword; Table of Contents; James 1. Mueller Memorial lecture High-Temperature Structural Silicides; High-Temperature Structural Silicides; Plenary Session; Advanced Ceramics in the U.S. for the 21st Century: Prospects and Challenges; High Performance Coatings; Synthesis and Characterization of Mullite and YAG Fibers Grown from Deeply Undercooled Melts; Solar Reflector Coatings for Space Applications; Passivation of Inner Surfaces of Chemical Process Reactor Tubes by Chemical Vapor Deposition; Ceramic Fibers and Whiskers |
Synthesis and Thermal Stability of a Si-N-(0) FiberFabrication and Mechanical Properties of Polymer Melt Spun Yttrium Aluminum Garnet (YAG) Fiber; Scaling Technology for Production of Continuous Ceramic Fiber; Piezoelectric Fibers Produced by the Fibrous Monolith Technique; Creep and Subcritical Crack Growth of Nextel 720 Alumino Silicate |
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Fibers As Received and After Heat Treatment at 1300°C; Microstructure and Interfacial Properties of Laser Ablation Coated, Fiber-Reinforced Ceramic Composite |
Thermal Stability and Chemical Corrosion Resistance of Newly Developed Continuous Si-Zr-CO Tyranno FiberOn the Statistical Strength of Nicalon Fibers and Its Characterization; Polymer Architecture and Crystallization Behavior of SiCN Fiber Precursors; High Temperature Contraction Behavior of Polymer-Derived Sic Fibers; Structure and Properties of SylramicTM Silicon Carbide Fiber-A Polycrystalline, Stoichiometric B-Sic Composition; Joining and Rapid Prototyping; Joining of Silicon Carbide Based Ceramics by Reaction Forming Approach |
Electrically Insulating Joining of Carbon-Carbon Composites for High-Temperature ApplicationsJoining Ceramic Composites Using Active MetaVHPCS Preceramic Polymer Slurries; Whisker-, Particulate-, and Nano-Composites; Intra-Granular Strengthening and Toughening by Brittle Nanoparticles in Ceramic Nanocomposites; Thermal Shock Resistance of Mullite and Mullite-ZrO2-Sic Whisker Composites; Grain Size Control and Phase Transformations in Nanophase Al2O3-ZrO2; Fracture Toughness and Reliability of Si3N4 Whisker-Reinforced Si3N4 Ceramics |
Sinter-Plus-HIPing of Zirconia and Zirconia Toughened Alumina (ZTA) Ceramic Matrix CompositesSpark-Erosion Process Effects on the Properties and Performance of a TiB2 Particulate-Reinforced/SiC Matrix Ceramic Composite; Solid Particle Erosion of an AI2O3-SIC-TIC Composite; Fractal Analysis of a Multilayered Composite DCB Specimen; Stress Relaxation Around Crack Tip in Ceramic Composites; Characterization of Grain-Boundary Fracture in Ceramics; Ceramic Composites: lnterfaces/lnterphases; Monazite Interface Coatings in Polymer and Sol-Gel Derived Ceramic Matrix Composites |
Isotropic Complex Oxides as Fiber Coatings for Oxide-Oxide CFCC |
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Sommario/riassunto |
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This volume is part of the Ceramic Engineering and Science Proceeding (CESP) series. This series contains a collection of papers dealing with issues in both traditional ceramics (i.e., glass, whitewares, refractories, and porcelain enamel) and advanced ceramics. Topics covered in the area of advanced ceramic include bioceramics, nanomaterials, composites, solid oxide fuel cells, mechanical properties and structural design, advanced ceramic coatings, ceramic armor, porous ceramics, and more. |
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4. |
Record Nr. |
UNINA9910131491503321 |
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Autore |
Brito Richard |
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Titolo |
Superradiance : Energy Extraction, Black-Hole Bombs and Implications for Astrophysics and Particle Physics / / by Richard Brito, Vitor Cardoso, Paolo Pani |
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Pubbl/distr/stampa |
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 |
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ISBN |
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Edizione |
[1st ed. 2015.] |
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Descrizione fisica |
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1 online resource (XIII, 237 p. 63 illus., 52 illus. in color.) |
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Collana |
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Lecture Notes in Physics, , 1616-6361 ; ; 906 |
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Disciplina |
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Soggetti |
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Gravitation |
Cosmology |
Elementary particles (Physics) |
Quantum field theory |
Classical and Quantum Gravity |
Elementary Particles, Quantum Field Theory |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Bibliographic Level Mode of Issuance: Monograph |
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Nota di contenuto |
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Introduction -- Superradiance in flat spacetime -- Superradiance in black hole physics -- Black holes and superradiant instabilities -- Black hole superradiance in astrophysics -- Conclusions and Outlook. |
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Sommario/riassunto |
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This volume gives a unified picture of the multifaceted subject of superradiance, with a focus on recent developments in the field, ranging from fundamental physics to astrophysics. Superradiance is a radiation enhancement process that involves dissipative systems. With a 60 year-old history, superradiance has played a prominent role in optics, quantum mechanics and especially in relativity and astrophysics. In Einstein's General Relativity, black-hole superradiance is permitted by dissipation at the event horizon, which allows energy extraction from the vacuum, even at the classical level. When confined, this amplified radiation can give rise to strong instabilities known as "blackhole bombs'', which have applications in searches for dark matter, in physics beyond the Standard Model and in analog models of gravity. This book discusses and draws together all these fascinating |
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aspects of superradiance. |
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