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Record Nr. |
UNINA9911009201403321 |
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Autore |
Halami Prakash M |
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Titolo |
Genome Editing in Bacteria (Part 1) |
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Pubbl/distr/stampa |
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Sharjah : , : Bentham Science Publishers, , 2024 |
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©2024 |
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ISBN |
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Edizione |
[1st ed.] |
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Descrizione fisica |
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1 online resource (201 pages) |
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Altri autori (Persone) |
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Soggetti |
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Gene editing |
Bacterial genetics |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Cover -- Title -- Copyright -- End User License Agreement -- Contents -- Foreword -- Preface -- List of Contributors -- Recent Advances in CRISPR-Cas Genome Engineering: An Overview -- Angelina Job Kolady1, Aritra Mukherjee1, Ranjith Kumavath1,2,*, Sarvepalli Vijay Kumar3 and Pasupuleti Sreenivasa Rao4,5,* -- INTRODUCTION -- GENOME EDITING -- GENOME EDITING TOOLS AND THEIR LIMITATIONS -- Restriction Enzymes (RE) -- Zinc Finger Nucleases (ZNFs) -- Transcription Activator Like Effector Nucleases -- Discovery and History -- Components of CRISPR-Cas -- Cas9 -- sgRNA and How to Design sgRNAs -- PAM Sequence -- Component CRISPR -- Component CRISPR (3C CRISPR) -- APPLICATION OF CRISPR -- Generation of Knockout -- Making Specific Modifications -- Combat Antimicrobial Resistance -- Genome Engineering in Agriculture -- Genome Engineering in Industrial Biotechnology -- FUTURE PERSPECTIVES OF CRISPR-CAS9 |
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Sommario/riassunto |
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This reference is a comprehensive review of genome editing in bacteria. The multi-part book meticulously consolidates research findings and insights on the applications of bacteria across several industries, including food processing and pharmaceutical development. The book covers four overarching themes for readers: a historical perspective of genome editing, genome editing in probiotics, applications of genome editing in agricultural microbiology and genetic engineering in |
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environmental microbiology. The editors have also compiled chapters that provide an in-depth analysis of gene regulation and metabolic engineering through genome editing tools for specific bacteria. Key topics in part 1: - An Overview of advances in CRISPR-CAS research - Applications of CRISPR/CAS9-based genome editing for industrial microorganisms - Gut microbiome modulation to address gut dysbiosis - Bifidobacterium genome editing for probiotic development and metabolic engineering. - Insights into the use of lactic acid bacteria as starter cultures in the food - Genome editing of vegetable-derived L. Plantarum - Genome editing in Bacillus Licheniformis Genome Editing in Bacteria is a definitive reference for scholars, researchers and industry professionals navigating the forefront of bacterial genomics. Readership Scholars and professionals interested in bacterial genomics. |
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