1.

Record Nr.

UNINA9911007090703321

Titolo

Designing multi-target drugs / / edited by J. Richard Morphy, C. John Harris

Pubbl/distr/stampa

Cambridge [England], : RSC Pub., 2012

ISBN

9781621981435

1621981436

9781849734912

1849734917

Edizione

[1st ed.]

Descrizione fisica

1 online resource (395 p.)

Collana

RSC drug discovery series, , 2041-3203 ; ; 21

Altri autori (Persone)

MorphyJ. Richard

HarrisC. John

Disciplina

615.19

Soggetti

Drug targeting

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

i-iv; v-x; xi-xiv; xv-xviii; xix-xxviii; 1-13; 14-31; 32-49; 50-65; 66-85; 86-93; 94-110; 111-129; 130-140; 141-154; 155-180; 181-205; 206-220; 221-242; 243-262; 263-269; 270-289; 290-315; 316-334; 335-352; 353-355; 356-366

Sommario/riassunto

Multi-target drug discovery (MTDD) is an emerging area of increasing interest to the drug discovery community. Drugs that modulate several targets have the potential for an improved balance of efficacy and safety compared to single targets agents. Although there are a number of marketed drugs that are thought to derive their therapeutic benefit by virtue of interacting with multiple targets, the majority of these were discovered accidentally. Written by world renowned experts, this is the first book to gather together knowledge and experiences of the rational discovery of multi-target drugs. I