Hypoxia and Tumor Microenvironment : Implications for Cancer Therapy / / edited by Sukhes Mukherjee, Jagat Rakesh Kanwar

• Record Nr.: UNINA9910988284803321
• Pubbl/distr/stampa: Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2025
• ISBN: 981-9610-16-8
• Edizione: [1st ed. 2025.]
• Descrizione fisica: 1 online resource (XIV, 236 p. 45 illus. in color.)
• Disciplina: 571.978; 616.994
• Soggetti: Cancer; Cancer - Treatment; Tumors - Immunological aspects; Tumor Microenvironment; Neoplasms - therapy; Tumor Hypoxia; Cancers; Cancer Therapy; Cancer Biology
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Nota di contenuto: -- Chapter 1: Tumor Hypoxia An Introduction -- Chapter 2: Hypoxia and tumor immunity -- Chapter 3: Incipient Role of Non coding RNAs in different types of cancer hypoxia -- Chapter 4: Hypoxia induced DNA damage response and genomic instability dictate cancer treatment response -- Chapter 5: Metabolic regulation of CAR T cell function by hypoxic tumor -- Chapter 6: Emerging roles of non coding RNAs in tumor hypoxia -- Chapter 7: Regulation of Angiogenesis by Cancer Hypoxia and Role of Hypoxia Inducible Factors with Therapeutic Paradigm -- Chapter 8: Hypoxia and Regulation of Cancer Cell Stemness -- Chapter 9: Hypoxia-Inducible Factors: Regulation and Therapeutic Potential in Cancer: Artificial Intelligence in Precision Medicine -- Chapter 10: Strategic application of bio reductive metalloprodrugs for cancer cell-selective anticancer therapy -- ; Chapter 11: Hypoxia Inducible Factors Regulation and Therapeutic Potential.
• Sommario/riassunto: This book provides a comprehensive overview of the hypoxic tumor microenvironment and its impact on various aspects of cancer biology, including DNA damage response, genome instability, tumor immunity, non-coding RNA regulation, metabolic regulation of CAR-T cell function, and angiogenesis. It explores the regulation and therapeutic potential of hypoxia-inducible factors, as well as strategies to improve cancer immunotherapy by targeting the hypoxic tumor microenvironment. This book is a valuable resource for students, researchers, and Medical science professionals interested in understanding the complex interplay between hypoxia and cancer biology.