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1. |
Record Nr. |
UNINA9910983388503321 |
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Autore |
Opdyke Aaron |
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Titolo |
Inclusive and Integrated Disaster Risk Reduction / / edited by Aaron Opdyke, Liberty Pascua de Rivera |
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Pubbl/distr/stampa |
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Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2025 |
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ISBN |
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Edizione |
[1st ed. 2025.] |
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Descrizione fisica |
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1 online resource (775 pages) |
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Collana |
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Springer Proceedings in Earth and Environmental Sciences, , 2524-3438 |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Natural disasters |
Climatology |
Geotechnical engineering |
Natural Hazards |
Climate Sciences |
Geotechnical Engineering and Applied Earth Sciences |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Measuring Social Vulnerability to Natural Hazards and Delineation of Natural Risk Zones in Indonesia -- Development of Local Level Storm Surge Hazard Maps for Potential Use in Storm Surge Evacuation and Development Planning -- Tsunami Spatial Vulnerability Index in Aceh Province 2020 using Remote Sensing and Geospatial Big Data -- Tsunami Hazard and Area Vulnerability of Mohammedia City in Morocco Simulation on the Reference Tsunami 1755 -- Monitoring Land Use and Land Cover Changes in Aceh Province-Indonesia for Sustainable Spatial Planning. |
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Sommario/riassunto |
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This book provides an interdisciplinary volume of advances in disaster science that further understanding global progress to reduce disaster risk. As we pass the halfway point on implementing the Sendai Framework for Risk Reduction, the question stands what progress has been made on reducing disaster risk at the global and local scales? The book is thematically grouped around the Sendai Framework’s four priorities, spanning efforts to assess hazards and risk, disaster |
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governance, mechanisms to build resilience, and recovery in the aftermath of crises. This book offers scholars and practitioners a glimpse into the opportunities and challenges at the forefront of disaster risk reduction efforts. |
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2. |
Record Nr. |
UNINA9910983345103321 |
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Titolo |
Introduction to surgical trials / / edited by Stephen Lyman, Olufemi R. Ayeni, Jason L. Koh, Norimasa Nakamura, Jón Karlsson |
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Pubbl/distr/stampa |
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Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , [2024] |
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ISBN |
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Edizione |
[First edition.] |
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Descrizione fisica |
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1 online resource (x, 215 pages) : illustrations |
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Collana |
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Disciplina |
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Soggetti |
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Surgery - Research |
Surgery - Research - Moral and ethical aspects |
Orthopedics |
Epidemiology |
Surgery |
Biometry |
Bioinformatics |
General Surgery - methods |
Clinical Trials as Topic |
Research Design |
Biostatistics |
Computational Biology |
Epidemiologic Research Design |
Orthopedic Procedures - methods |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references. |
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Nota di contenuto |
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SECTION A: Trial Design -- Why Do We Need Surgical Trials? -- Addressing the Challenges to Surgical Randomization -- |
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Randomization Strategies -- Surgical Trial Design: Interventions & Blinding -- Sample Size and Power Considerations for Surgical Trials -- Optimizing Recruitment in Randomized Controlled Trials -- Treatment Allocation -- Crossover and early failure in surgical trials -- Strategies to Optimize Follow-up in Surgical Trials -- Considerations in Choosing Outcomes Measures -- Length of Follow-Up -- SECTION B: Conducting a Trial -- Ethics considerations and approval in human research and in orthopaedics -- Trial Start Up Considerations: Budget, Staffing, Logistics -- Adverse Events Reporting & Data and Safety MonitoringTrial Closeout -- SECTION C: Trial Completion -- Missing Data & Imputation -- Statistical Analysis for Surgical Trials -- CONSORT Reporting Standards -- SECTION D: Regulatory Standards -- The Regulatory Pathway to Market Class III Surgical Medical Devices in the United States -- European Standards -- Regulatory Standards for Surgical Trials in Asia: the Japanese Experience -- SECTION E: Alternatives to the Classic RCT -- Pragmatic TrialsPlatform Trials -- Prospecitve Cohort StudiesSurgical Registries -- The Future of Trials. |
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Sommario/riassunto |
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Filling a gap in literature, this book examines surgical trials with a special focus on the underlying principles, challenges, and best practices to successfully conduct rigorous surgical research. While randomized controlled trials (RCTs) remain the gold standard for evaluation of the safety and efficacy of most medical interventions, they are particularly difficult to implement successfully in the context of surgery. As a result, recruitment rates are often extremely low, crossover from non-operative to operative is common, and patients randomly allocated to surgery often simply decline to have the procedure. All of these challenges call into question the recent generalizability and fundamental quality of traditional surgical RCTs. As such, this book explores advanced alternative trial design methods and describes the current regulatory environment around the world. Designed as a practical guide, it is a valuable tool for surgeons, epidemiologist and biostatisticians involved in this challenging field. |
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