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1. |
Record Nr. |
UNINA9910983082803321 |
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Autore |
Sørlie Therese |
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Titolo |
A Guide to Breast Cancer Research : From Cellular Heterogeneity and Molecular Mechanisms to Therapy / / edited by Therese Sørlie, Robert B. Clarke |
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Pubbl/distr/stampa |
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Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2025 |
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ISBN |
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Edizione |
[1st ed. 2025.] |
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Descrizione fisica |
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1 online resource (926 pages) |
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Collana |
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Advances in Experimental Medicine and Biology, , 2214-8019 ; ; 1464 |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Cancer |
Oncology |
Cancer - Treatment |
Metastasis |
Tumors - Immunological aspects |
Cancer Biology |
Cancer Therapy |
Tumour Immunology |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Part I: Development and cancer: basic concepts -- Chapter 1: Introductory chapter by Sorlie and Clarke -- Chapter 2: Embryonic mammary gland morphogenesis -- Chapter 3: Breast morphogenesis: from normal development to cancer -- Chapter 4: Single-Cell Analysis in the Mouse and Human Mammary Gland -- Part II: Development and cancer: model systems and approaches -- Chapter 5: Recording lineage history with cellular barcodes in the mammary epithelium and in breast cancer -- Chapter 6: Models for studying ductal carcinoma in situ progression -- Chapter 7: Patient-derived xenografts of breast cancer -- Chapter 8: Rat Models of Breast Cancer -- Part III: Development and cancer: cells of origin and heterogeneity -- Chapter 9: Cells of origin of breast cancer and intertumoral heterogeneity -- Chapter 10: |
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Mechanisms of regulation of cell fate in breast development and cancer -- Chapter 11: Classification of breast cancer through the perspective of cell identity models -- Part IV: Cellular and molecular basis -- Chapter 12: The Microenvironment in DCIS and its Role in Disease Progression -- Chapter 13: Molecular basis of breast tumor heterogeneity -- Chapter 14: E-cadherin-mediated cell-cell adhesion and invasive lobular breast cancer -- Part V: Signalling pathways -- Chapter 15: Hormone signaling in breast development and cancer -- Chapter 16: RANK/RANKL signaling pathway in breast development and cancer -- Chapter 17: Metabolic Reprogramming and Adaption in Breast Cancer Progression and Metastasis -- Part VI: Metastasis and immunity -- Chapter 18: Microenvironmental regulation of dormancy in breast cancer metastasis: “An ally that changes allegiances” -- Chapter 19: The Roles of Myeloid Cells in Breast Cancer Progression -- Chapter 20: Immune microenvironment in breast cancer metastasis -- Part VII: Subtypes, treatment and resistance -- Chapter 21: Clinical Implications of Breast Cancer Intrinsic Subtypes -- Chapter 22: Targeting Estrogen Receptor signalling in breast cancer therapy -- Chapter 23: CDK4/6 inhibitor resistance in ER+ breast cancer -- Chapter 24: HER2-positive breast cancer treatment and resistance. |
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Sommario/riassunto |
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The book presents key topics at the forefront in breast development and cancer research in chapters authored by leading scientists in the field. The chapters provide a basis for understanding major concepts, model systems, cells of origin and heterogeneity in human breast development and cancer. The book builds on this understanding to guide readers through the cellular and molecular basis of breast cancer and the most important signaling pathways. Finally, the book describes mechanisms of metastasis and cancer immunity, and treatment options and resistance to therapy. It is targeted at young scientists and early career researchers and provides an overview of current topics in breast cancer research. Each chapter includes key learning points, boxes and conclusions to highlight the most important information. This book will interest anyone who wants to learn about the main areas of breast cancer research and the most important recent advances. |
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2. |
Record Nr. |
UNISANNIOAQ10007617 |
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Autore |
Hernández, Daniel <1961- > |
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Titolo |
Qualitative representation of spatial knowledge / Daniel Hernández |
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Pubbl/distr/stampa |
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Berlin [etc.], : Springer, c1994 |
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Descrizione fisica |
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Collana |
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Lecture notes in computer science / edited by G. Goos and J. Hartmanis , . Lecture notes in artificial intelligence ; 804 |
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Disciplina |
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Soggetti |
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Intelligenza artificiale |
Statistica - Metodi matematici |
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Collocazione |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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3. |
Record Nr. |
UNINA9910973602103321 |
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Titolo |
Korea yearbook / / edited by Rüdiger Frank ... [et al.] ; associate editors, Charles Armstrong ... [et al.] |
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Pubbl/distr/stampa |
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ISBN |
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Descrizione fisica |
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1 online resource (382 p.) |
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Collana |
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Korea 2011 : politics, economy and society, , 1875-0273 ; ; v. 5 |
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Altri autori (Persone) |
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FrankRüdiger <1969-> |
ArmstrongCharles |
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Disciplina |
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Soggetti |
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Korea Politics and government |
Korea Economic conditions |
Korea Social conditions |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references. |
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Nota di contenuto |
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Preliminary Material -- List of Refereed Articles Published since 2007 -- Chronology of Events in the Korean Peninsula 2010 -- South Korea in 2010: Domestic Politics and the Economy / Patrick Köllner -- North Korea in 2010: Domestic Developments and the Economy / Rüdiger Frank -- Relations Between the Two Koreas in 2010 / Sabine Burghart -- Foreign Relations of the Two Koreas in 2010 / James E. Hoare -- Nation Branding in South Korea: A Modern Continuation of the Developmental State? / Alena Schmuck -- From ‘Cold Friendship’ to Strategic Partnership: The Transformation of South Korea’s Political Relations with India / Niclas D. Weimar -- Shopping Abroad the Korean Way: A Study in Resource Acquisition / Stefania Paladini -- Managing Labour Migration to South Korea: Policies and Problems Regarding Migrant Workers / Sarah Hasan -- Vil(l)e Encounters: The US Armed Forces in Korea and Entertainment Districts in and near Seoul / Elisabeth Schober -- A Trajectory Perspective Towards Return Migration and Development: The Case of Young Korean New Zealander Returnees / Jane YeonJae Lee -- Connecting East Asians in Europe: The Power of Korean Popular Culture / Sang-Yeon Sung -- From the ‘Soviet Era’ to the ‘Russian Renaissance’: Evolution of the Narrative about Russia and Russians in the North Korean Cultural Discourse / Tatiana Gabroussenko -- Beyond Lips and Teeth: The Economics of the China- |
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North Korea Relationship / Tim Beal -- The International Community and the North Korean Nuclear Programme / Sebastian Harnisch and David J. Roesch -- About the Authors and Editors -- Map of the Korean Peninsula. |
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Sommario/riassunto |
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This book is the fifth in an annual series. It provides up-to-date information on the politics, economy and society of both South and North Korea. Each volume is structured as follows: The first part offers the reader an up-to-date analysis and commentary on the following topics: \'Domestic Politics and the Economy in South Korea\', \'Domestic Politics and the Economy in North Korea\', \'Relations between the two Koreas\', and \'Foreign Relations of the two Koreas\'. A detailed chronology of relevant events in the year preceding publication complements this first part. The second part consists of some eight to ten refereed, original articles with contributions on contemporary Korean affairs in fields such as politics, economy and society. For regular and professional observers of Korea in business, politics, the media and academia, this book series is an indispensable resource both for keeping track of developments, and for gathering new insights. |
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