Cell mechanics : from single scale-based models to multiscale modeling / / edited by Arnaud Chauviere, Luigi Preziosi, Claude Verdier

• Record Nr.: UNINA9910972038203321
• Pubbl/distr/stampa: Boca Raton, : Chapman & Hall/CRC, c2010
• ISBN: 1-04-020908-4; 0-429-14709-0; 1-282-49554-2; 9786612495540; 1-4200-9455-6
• Edizione: [1st ed.]
• Descrizione fisica: 1 online resource (484 p.)
• Collana: Chapman & Hall/CRC mathematical and computational biology series
• Altri autori (Persone): ChauviereArnaud; PreziosiLuigi; VerdierClaude <1962->
• Disciplina: 571.6
• Soggetti: Cells - Mechanical properties - Mathematical models; Cells - Mechanical properties - Computer simulation; Tumors - Growth - Mathematical models; Tumors - Growth - Computer simulation
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Front cover; Part I: From Subcellular to Cellular Properties; Chapter 1. Microhenology of Living Cells at Different Time and Length Scales; Chapter 2. Actin-Based Propulsion: Intriguing Interplay between Material Properties and Growth Processes; Chapter 3. Cancer: Cell Motility and Tumor Suppessor Genes; Part II: Single Cell Migration Modeling; Chapter 4. Coupling of Cytoplasm and Adhesion Dynamics Determines Cell Polarization and Locomotion; Chapter 5. How Do Cells Move? Mathematical Modeling of Cytoskeleton Dynamic and Cell Migration; Chapter 6. Computational Framework Integrating Cytoskeletal and Adhesion Dynamics for Modeling Cell MotilityPart III: Mechanical Effects of Environment on Cell Behavior; Chapter 7. History Dependence of Mocrobead Adhesion under Varying Shear Rate; Chapter 8. Understanding Adhesion Sites as Mechanosensitive Cellular Elements; ; Chapter 9. Cancer Cell Migration on 2-D Deformable Substrates; Chapter 10. Single-Cell Imaging of Calcium in Response to Mechanical Stimulation; Part IV: From Cellular to Multicellular Models; Chapter 11. Mathematical Framework to Model Migration of Cell Population in Extracellular MatrixChapter 12. Mathematical Modeling of Cell Adhesion and Its Applications to Developmental Biology and Cancer Invasion; Chapter 13. Bridging Cell and Tissue Behavior in Embryo Development; Chapter 14. Modeling Steps from Benign Tumor to Invasion Cancer: Examples of Intrinsically Multiscale Problems; Chapter 15. Delaunay Object Dynamics for Tissues Involving Highly Motile Cells; Index; Back cover
• Sommario/riassunto: Ubiquitous and fundamental in cell mechanics, multiscale problems can arise in the growth of tumors, embryogenesis, tissue engineering, and more. This book discusses the tool of microrheology for investigating cell mechanical properties, and multiphysics and multiscale approaches for studying intracellular mechanisms in cell motility.