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1. |
Record Nr. |
UNINA9910688354903321 |
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Titolo |
CRISPR Technology : recent advances / / edited by Yuan-Chuan Chen |
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Pubbl/distr/stampa |
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London : , : IntechOpen, , 2023 |
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©2023 |
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Descrizione fisica |
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1 online resource (158 pages) |
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Disciplina |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Preface -- Section 1 Introduction -- Chapter 1 Introductory Chapter: CRISPR Technology by Yuan-Chuan Chen -- Chapter 2 Emerging CRISPR Technologies by Annelise Cassidy and Stephane Pelletier -- Section 2 Technology -- Chapter 3 Maximizing the Efficacy of CRISPR/Cas Homology-Directed Repair Gene Targeting by Terry S. Elton, Md. Ismail Hossain, Jessika Carvajal-Moreno, Xinyi Wang, Dalton J. Skaggs and Jack C. Yalowich -- Chapter 4 The Prominent Characteristics of the Effective sgRNA for a Precise CRISPR Genome Editing by Reza Mohammadhassan, Sara Tutunchi, Negar Nasehi, Fatemeh Goudarziasl and Lena Mahya -- Chapter 5 Recent Advances in In Vivo Genome Editing Targeting Mammalian Preimplantation Embryos by Masahiro Sato, Masato Ohtsuka, Emi Inada, Shingo Nakamura, Issei Saitoh and Shuji Takabayashi -- Section 3 Application -- Chapter 6 Applications of CRISPR/Cas9 for Selective Sequencing and Clinical Diagnostics by Maximilian Evers, Björn Brändl, Franz-Josef Müller, Sönke Friedrichsen and Stephan Kolkenbrock. |
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Sommario/riassunto |
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CRISPR technology has been extensively used in vitro and in vivo as a tool in basic research for genetic editing (e.g., genome encoding, silencing, enhancing, and modification). Although there are many technical and ethical challenges to overcome, such as off-target effects, delivery tool selection, and safety concerns, scientists are working to improve this technology. CRISPR technology is promising for practical applications as well as for laboratory work and basic research. |
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Currently, CRISPR is being used successfully in microbial detection, disease diagnosis, and manufacturing of agricultural products, food, industrial products, and medicinal products. The development of medicinal products using CRISPR will open a new era for human therapeutics and may bring hope for the recovery of ill patients. This book provides a comprehensive overview of CRISPR technology. It examines its discovery, improvement, and implications, explores its technology and applications, and discusses perspectives and challenges. |
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2. |
Record Nr. |
UNINA9910971096603321 |
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Autore |
Marl Katie <1974-> |
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Titolo |
The accessible games book / / collated and adapted by Katie Marl |
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Pubbl/distr/stampa |
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London ; ; Philadelphia, : Jessica Kingsley Publishers, 1999 |
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ISBN |
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9786610537969 |
9781280537967 |
1280537965 |
9781846421563 |
184642156X |
9781417552825 |
1417552824 |
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Edizione |
[[New ed.].] |
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Descrizione fisica |
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1 online resource (112 p.) |
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Disciplina |
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Soggetti |
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Children with disabilities - Recreation |
People with disabilities - Recreation |
Educational games |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Previous ed.: 1996. |
Includes index. |
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Nota di contenuto |
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Intro -- The Accessible Games Book -- Contents -- Introductory games -- Limited sight -- Limited hearing -- Limited mobility -- Limited upper body strength and mobility. |
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Sommario/riassunto |
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This book contains games for mixed groups including people with auditory or visual impairments, those in wheelchairs, and those with multiple disabilities. The games can also be used as a means of improving disability awareness among the non-disabled, and have been used successfully with groups of people of all abilities and ages. |
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