1.

Record Nr.

UNINA9910810069203321

Autore

Gallez Louise

Titolo

Voorspoed en tegenspoed van een verplegster op spoed : Getuigenis / / Louise Gallez

Pubbl/distr/stampa

Cork : , : Primento Digital Publishing, , 2018

ISBN

2-39009-317-5

Descrizione fisica

1 online resource (127 pages)

Disciplina

121.3

Soggetti

Testimony (Theory of knowledge)

Lingua di pubblicazione

Francese

Formato

Materiale a stampa

Livello bibliografico

Monografia

2.

Record Nr.

UNINA9910970099403321

Titolo

Molecular biology of Alzheimer's disease : genes and mechanisms involved in amyloid generation / / edited by Christian Haass

Pubbl/distr/stampa

Amsterdam, The Netherlands, : Harwood Academic Publishers, c1998

ISBN

0-429-07779-3

1-4822-8345-X

1-280-05339-9

9786610053391

0-203-30361-X

Edizione

[1st ed.]

Descrizione fisica

1 online resource (350 p.)

Altri autori (Persone)

HaassChristian

Disciplina

616.831

Soggetti

Alzheimer's disease - Genetic aspects

Alzheimer's disease - Molecular aspects

Amyloid beta-protein precursor

Molecular neurobiology

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia



Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Book Cover; Title; Contents; Contributors; Introduction; Amyloid Morphology and Pathology of Alzheimer's Disease; The Tau Proteins in Alzheimer's Disease; Mutations in Three Genes are Associated with Early Onset Alzheimer's Disease; The Biological Activities and Function of the Amyloid Precursor Protein  of Alzheimer's Disease; Proteolytic Processing of the -Amyloid Precursor Protein; Biosynthesis of APP and A: Multiple Pathways for the Generation of  Intracellular A; The Cell Biology of Amyloid Precursor Protein

The Role of Amyloid -Peptide Terminating at Amino Acid 42 in Early  Onset Alzheimer's DiseaseThe Biophysics of Amyloid -Protein Fibrillogenesis; The Molecular Biology of Presenilin 1; Molecular Biology of Presenilin 2; Presenilin Proteins and their Role in Development and Notch Signaling; The Processing of the Amyloid-Precursor-Protein (APP) in Presenilin-1  Deficient Neurons; Presenilins and their Role in Apoptosis; The Phosphorylation of Presenilin Proteins; APOE and its Role in Late Onset Alzheimer's Disease

Transgenic Animal Models in the Development of Therapeutic Strategies  for Alzheimer's DiseasePresenilins in Transgenic Mice; Index

Sommario/riassunto

Highlighting the latest and the most timely aspects of Alzheimer's disease research, this text will enable scientists in related research fields, as well as physicians working with Alzheimer's disease patients, to obtain a quick and complete overview of the current state of the art in one of the most exciting fields in neuroscience research. Leading scientists have contributed articles focusing on key developments in this field. This includes an overview about the pathology, the genetics of familial Alzheimer's disease, proteolytic generation and aggregation of amyloid -peptide, presenilins, r