1.

Record Nr.

UNINA9910969164803321

Titolo

Acute lymphoblastic leukemia : etiology, pathogenesis and treatments / / Severo Vecchione and Luigi Tedesco, editors

Pubbl/distr/stampa

New York, : Nova Science Publishers, Inc., c2012

ISBN

1-61470-905-X

Edizione

[1st ed.]

Descrizione fisica

1 online resource (251 p.)

Collana

Cancer etiology diagnosis and treatments

Altri autori (Persone)

VecchioneSevero

TedescoLuigi

Disciplina

616.99/419071

Soggetti

Lymphoblastic leukemia

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

"Nova biomedical."

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Genome wide association studies in pediatric acute lymphoblastic leukemia : pathogenesis and therapy / Kyriaki Hatziagapiou ... [et al.] -- Mice deficient for the Slp65 signaling protein : a model for Pre-B cell acute lymphoblastic leukemia / Van B.T. Ta, Rudi W. Hendriks -- Childhood acute lymphoblastic leukemia / Adriana Zámecníkova -- Systems approaches to childhood leukemogenesis / George I. Lambrou -- Histone deacetylase inhibitors : pre-clinical and clinical evidence in treating acute lymphoblastic leukemia / Ana Lucia Abujamra -- A therapeutic target in leukemia : the NK-1 receptor / Miguel Muñoz, Ana González-Ortega, Rafael Coveñas -- Minimal residual disease monitoring in childhood acute lymphoblastic leukemia / Katerina Katsibardi -- Clinical relevance and application of cytogenetic approaches in pediatric acute lymphoblastic leukaemia / Maria Braoudaki -- Maintenance therapy in Ph negative adult acute lymphoblastic leukemia / Michael Doubek, Jirí Mayer -- The role of innate and adaptive immunity in childhood acute lymphoblastic leukemia / Maria Hatzistilianou, Agiou Ioannou.

Sommario/riassunto

Acute lymphoblastic leukemia (ALL) is a malignant disorder of the bone marrow in which a lymphoid precursor cell becomes genetically altered resulting in dysregulated proliferation and clonal expansion of neoplastic cells. It is the most common malignancy in children, representing nearly one third of all pediatric cancers. In this book, the authors present topical research in the study of acute lymphoblastic



leukemia including genome wide association studies in pediatric acute lymphoblastic leukemia; mice deficient for the Slp65 signaling protein which is a model for ALL; histone deacetylase inhibitors and maintenance therapy in Ph negative adult acute lymphoblastic leukemia.

2.

Record Nr.

UNINA9910969975103321

Autore

Lowe John <1934->

Titolo

Britain and foreign affairs, 1815-1885 : Europe and overseas / / John Lowe

Pubbl/distr/stampa

London ; ; New York, : Routledge, 1998

ISBN

1-134-77780-9

1-280-14930-2

9786610149308

0-203-98438-2

Descrizione fisica

1 online resource (113 p.)

Collana

Lancaster pamphlets

Disciplina

327.4104

Soggetti

International relations

Great Britain Foreign relations 19th century

Great Britain Foreign relations Europe

Europe Foreign relations Great Britain

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references.

Nota di contenuto

Preliminaries; Contents; Foreword; 1 The making of British foreign policy 1815 85; 2 Castlereagh and Canning 1815 27; 3 The Palmerstonian age 1830 65; 4 The Gladstone Disraeli era 1866 85; 5 Conclusion; Select bibliography

Sommario/riassunto

This pamphlet examines British foreign policy from Castlereagh to Disraeli. Focusing on Britain's relations with other European and non-European powers such as America, Afghanistan, South Africa and Egypt, this pamphlet examines the roles of Canning, Palmerston, and Gladstone amongst others. The author discusses British attitudes to empire, and analyses socio-economic, military and political factors as



they influenced foreign affairs.