1.

Record Nr.

UNINA9910969143103321

Autore

White Robert J. <1963->

Titolo

Gene transcription : mechanisms and control / / Robert J. White

Pubbl/distr/stampa

London ; ; Malden, MA, : Blackwell Science, 2001

ISBN

9786612117602

9781282117600

1282117602

9781444311365

1444311360

Edizione

[1st ed.]

Descrizione fisica

1 online resource (290 p.)

Disciplina

572.8/845

Soggetti

Genetic transcription

Genetic transcription - Regulation

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Gene Transcription Mechanisms and Control; Contents; Preface; Abbreviations; Chapter 1: Introduction; Chapter 2: The Nuclear RNA Polymerases; Chapter 3: DNA Recognition by Transcription Factors; Chapter 4: Basal Transcription by RNA Polymerase II; Chapter 5: Activating RNA Polymerase II Transcription; Chapter 6: Transcription by RNA Polymerase I; Chapter 7: Transcription by RNA Polymerase III; Chapter 8: The Influence of Chromatin on Transcription; Chapter 9: Controlling Transcription Factor Production; Chapter 10: Regulation of Transcription Factor Localization

Chapter 11: Regulation of Transcription Factor ActivityChapter 12: Cell Cycle Regulation of Transcription; Chapter 13: Interactions Between Transcription and Other Nuclear Processes; Chapter 14: Transcription Factors and Development; Index

Sommario/riassunto

Transcription is the focus of much cutting-edge research, as befits its essential place in biology. The established link between defects in gene transcription and many human disorders has fuelled considerable activity in the biomedical arena, particularly cancer research. This concentration of attention has uncovered a myriad of factors involved in transcription and the literature is now rife with jargon and



complexity.  Gene Transcription: Mechanisms and Control aims to demystify the subject for a non-expert audience, providing a guided tour around the complex machinery of the transc